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  4. Recombinant Xenopus laevis Paired box protein Pax-8 (pax8)

Recombinant Xenopus laevis Paired box protein Pax-8 (pax8)

  • 货号：
    CSB-YP879377XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP879377XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP879377XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP879377XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP879377XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    pax8; pax-8Paired box protein Pax-8; XPax-8
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-465
  • 氨基酸序列
    MPNSSIRSEL TTERGFSGPA SNFNIGHGGL NQLGGAFVNG RPLPEVVRQR IVDLAHQGVR PCDISRQLRV SHGCVSKILG RYYETGSIRP GVIGGSKPKV ATPKVVEKIG DYKRQNPTMF AWEIRDRLLT DGVCDNDTVP SVSSINRIIR TKVQQLFNLP MESCVKSLSP GQTLIPSSTV TPPESPHSDS LGSTYSISGL LGITQPSADG KRKLDDSDQE SCRLSIDSQG SVGISRKQLR TEAYGHHPLD ALECHFQRQH FPESYSSSTH SKTEQALYTL PLLNISLDDG KSSLTSTNTT IGRNLSTHQG YSALSEFTAF SIKQEASDSS SASSTPSSLC SPTFLDLQPI NSGCSAPSFS AFSHPSVYGQ FTSHVASGRD VVGATLPGYP PHIPSGQGNY ASSAIAGMVA AGGDYSANAY SHGAYAAYGD SWRFPSSSLL GSPYYYSSGT RTAPPPTTAG AYDLM
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 to establish the pronephric primordium in late gastrulae/early neurulae.
  • 基因功能参考文献：
    1. Pax8 is required for cell proliferation of pronephric precursors and regulates the expression of hnf1b and wnt pathway genes in the kidney field. PMID: 25446030
    2. nephrogenic transcription factors (osr1, osr2, hnf1b, lhx1, pax8)play important role in nephrogenesis but have no pronephros induction potential upon overexpression; they activate transcription cascades reflecting activation by activin A, retinoic acid PMID: 21281489
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expression starts at late gastrula stages in cells fated to become the primordia of the otic system and the pronephric kidney. Expression is maintained in these two structures through late tailbud stages. Does not appear to be expressed in the thyroid gla
  • 数据库链接：

    KEGG: xla:398132

    UniGene: Xl.2754