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  4. Recombinant Xenopus laevis Protein arginine N-methyltransferase 1-B (prmt1-b)

Recombinant Xenopus laevis Protein arginine N-methyltransferase 1-B (prmt1-b)

  • 中文名称：
    有爪蟾蜍prmt1-b重组蛋白
  • 货号：
    CSB-YP754434XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    有爪蟾蜍prmt1-b重组蛋白
  • 货号：
    CSB-EP754434XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    有爪蟾蜍prmt1-b重组蛋白
  • 货号：
    CSB-EP754434XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    有爪蟾蜍prmt1-b重组蛋白
  • 货号：
    CSB-BP754434XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    有爪蟾蜍prmt1-b重组蛋白
  • 货号：
    CSB-MP754434XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    prmt1-b
  • Uniprot No.：
  • 别名：
    prmt1-b; prmt1; prmt1bProtein arginine N-methyltransferase 1-B; xPRMT1b; EC 2.1.1.319; Arginine methyltransferase 1b; Histone-arginine N-methyltransferase PRMT1-B
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-351
  • 氨基酸序列
    MAEAKTCNME VSCALPEGSV KPNAEDMTSK DYYFDSYAHF GIHEEMLKDE VRTLTYRNSM FHNRHLFKDK VVLDVGSGTG ILCMFAAKAG AKKVIGIECS SISDYAIKIV KANKLDHVVT IIKGKVEEVE LPVEKVDIII SEWMGYCLFY ESMLNTVIYA RDKWLNPDGL IFPDRATLYV TAIEDRQYKD YKIHWWENVY GFDMSCIKDV AIKEPLVDVV DPKQLVSNAC LIKEVDIYTV KVDDLTFTSP FCLQVKRNDY IHAMVAYFNI EFTRCHKRTG FSTSPESPYT HWKQTVFYME DYLTVKTGEE IFGTISMKPN AKNNRDLDFT VDIDFKGQLC ELSCSTDYRM R
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in target proteins. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Methylates ilf3 to regulate its DNA-binding activity. Required for neural induction, playing a key role in the control of epidermal versus neural cell fate choice.
  • 基因功能参考文献：
    1. results describe the role of calcium and the arginine methyltransferase xPRMT1b in the embryonic determination of epidermal or neural cell fate PMID: 16214893
  • 亚细胞定位：
    Nucleus. Nucleus, nucleoplasm. Cytoplasm, cytosol. Cytoplasm.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family
  • 组织特异性：
    From the onset of gastrulation, expressed in dorsal mesoderm, and in dorsal and ventral ectoderm. At the neurula and tail bud stages, expression is restricted to the neuroectoderm, with highest expression in the anterior neural plate.
  • 数据库链接：

    KEGG: xla:398716

    UniGene: Xl.29799