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  4. Recombinant Xenopus laevis Transcription factor Sox-7 (sox7)

Recombinant Xenopus laevis Transcription factor Sox-7 (sox7)

  • 中文名称：
    有爪蟾蜍sox7重组蛋白
  • 货号：
    CSB-YP022435XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    有爪蟾蜍sox7重组蛋白
  • 货号：
    CSB-EP022435XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    有爪蟾蜍sox7重组蛋白
  • 货号：
    CSB-EP022435XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    有爪蟾蜍sox7重组蛋白
  • 货号：
    CSB-BP022435XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    有爪蟾蜍sox7重组蛋白
  • 货号：
    CSB-MP022435XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    sox7
  • Uniprot No.：
  • 别名：
    sox7; Transcription factor Sox-7; xSOX7
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-362
  • 氨基酸序列
    MTTLMGSYSW TESLDCSPMD GDLSDGLSPH RSPREKGSET RIRRPMNAFM VWAKDERKRL AVQNPDLHNA ELSKMLGKSW KALSPAQKRP YVEEAERLRV QHMQDYPNYK YRPRRKKQIK RICKRVDTGF LLGSLSKDQN SVPDTRGCRT AMEKEENGGY PGAALSDIRH YRETPSNGNK YDQTYPYGLP TPPEMSPLEA IDQDQSFYST SCSEDCHSHI NGAVYPPEYS RSPILCSHLS QVPIPQPGSS MIPPVPTCPP AYYSSSYHSI HNYHAHLGQL SPPPEHPHYD TIDQISQAEL LGEMDRNEFD QYLNTSLQDP TEMTIHGHVQ VSQASDIQPS ETSLISVLAD ATATYYNSYS VS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor. Binds to the DNA sequence 5'-AACAAT-3'. Acts downstream of vegt and upstream of nodal signaling to promote endodermal and mesodermal differentiation by promoting vegt-induced expression of both endodermal genes (including endodermin) and mesodermal genes (including snai1/snail and snai2/slug). Induces expression of multiple nodal genes (including nodal, nodal2, nodal4, nodal5 and nodal6) and binds directly to sites within the promoter of the nodal5 gene. The endodermal and mesodermal specification pathways then interact to initiate cardiogenesis. Acts partially redundantly with sox18 during cardiogenesis. Also acts as an antagonist of beta-catenin signaling. Regulates (possibly indirectly) development of the pronephros, the functional larval kidney.
  • 基因功能参考文献：
    1. SOX7 mRNA is localized to the vegetal region of the blastula-stage embryo PMID: 15680368
    2. SOX7 and SOX18b are essential regulators of cardiogenesis in Xenopus. PMID: 16193513
    3. Vegetal pole localized Sox7 positively regulates Nodal (Xnr4, Xnr5, and Xnr6) expression, as well as the expression of genes involved in mesodermal (Xmenf, Slug, and Snail) and endodermal (Endodermin and Sox17beta) differentiation. PMID: 17608734
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Localized to the vegetal hemisphere of blastula embryos. Tissue-specific expression in early neurula (stage 13-14) embryos begins in the ciliate cells of the epidermis. Starting about stage 24, expression is found in a lateral stripe on each side of the e
  • 数据库链接：

    KEGG: xla:378665

    UniGene: Xl.1241