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  4. Recombinant Xenopus laevis Twisted gastrulation protein homolog 1-A (twsg1-a)

Recombinant Xenopus laevis Twisted gastrulation protein homolog 1-A (twsg1-a)

  • 中文名称：
    有爪蟾蜍twsg1-a重组蛋白
  • 货号：
    CSB-YP860315XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    有爪蟾蜍twsg1-a重组蛋白
  • 货号：
    CSB-EP860315XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    有爪蟾蜍twsg1-a重组蛋白
  • 货号：
    CSB-EP860315XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    有爪蟾蜍twsg1-a重组蛋白
  • 货号：
    CSB-BP860315XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    有爪蟾蜍twsg1-a重组蛋白
  • 货号：
    CSB-MP860315XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    twsg1-a
  • Uniprot No.：
  • 别名：
    twsg1-a; tsg; Twisted gastrulation protein homolog 1-A
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    26-216
  • 氨基酸序列
    CNKAL CASDVSKCLI QELCQCRPTD GNCSCCKECM LCLGTLWDEC CDCVGMCKPR NYSDTPPTSK STVEELHEPI PSLFRALTEG DTQLNWNIVT FPVVEELSHH ENLVSFLENV NQPQNVSVQV SHSNEKEHMC TVVYFDDCMS IHQCKVSCES MGASKYRWFH NACCECVGPE CIDYGSKTVK CVNCMV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in dorsal-ventral patterning, permitting peak BMP signaling by antagonizing the residual anti-BMP activity of the cleavage products of chrd. Functions to promote the formation of ventral mesoderm by increasing the activity of bmp7 and other BMPS. Seems to antagonize BMP signaling by forming ternary complexes with chrd and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of chrd, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation.
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Twisted gastrulation protein family
  • 组织特异性：
    Posterior defects are induced by overexpression. This may arise through alteration of bmp4 or chrd function in the developing tailbud region.
  • 数据库链接：

    KEGG: xla:399387

    UniGene: Xl.778