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  4. Recombinant Xenopus laevis Wilms tumor protein homolog A (wt1-a)

Recombinant Xenopus laevis Wilms tumor protein homolog A (wt1-a)

  • 中文名称：
    有爪蟾蜍wt1-a重组蛋白
  • 货号：
    CSB-YP491526XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    有爪蟾蜍wt1-a重组蛋白
  • 货号：
    CSB-EP491526XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    有爪蟾蜍wt1-a重组蛋白
  • 货号：
    CSB-EP491526XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    有爪蟾蜍wt1-a重组蛋白
  • 货号：
    CSB-BP491526XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    有爪蟾蜍wt1-a重组蛋白
  • 货号：
    CSB-MP491526XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    wt1-a
  • Uniprot No.：
  • 别名：
    wt1-a; wt1; Wilms tumor protein homolog A; XWT1a; xWT1
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-414
  • 氨基酸序列
    MGSDVRDMNL LPPVSSLSGN SSCNMPVSSS AQWAPVLDFP PGAPYSSLTP HSFIKQEPTW NPDPHEDQCL SAFTVHFSGQ FTGTAGACRY GPFGAPTPSQ ATTGQARMFS NAPYLSNCLD NQQGMRNQGY SAVAFDGTPS YGHTPSHHTS QFTNHSFKHE DPLSQQTSLG EQQYSVPPPV YGCHTPTDTC TGSQALLLRT PYNSDNLYPM TSQLDCMTWN QMNLGSSLKS HGTSYENDSH SSPMLYNCGG QYRIHTHGVF RGIQDVRRVP GVTPAIVRST EANEKRPFMC AYPGCNKRYF KLSHLQMHSR KHTGEKPYQC DFKDCERRFS RSDQLKRHQR RHTGIKPFQC KTCQRKFSRS DHLKTHTRTH TGKTSEKPFS CRWPSCQKKF ARSDELVRHH NMHQRNMTKL QLAL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor required for development of the vascular component of the pronephric kidney, the glomus; may repress tubule-specific gene expression in the portion of the pronephros fated to form the glomus. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Inhibits Wnt-signaling during embryonic development. Function may be isoform-specific: the isoform containing the KTS motif is less effective in inhibiting wnt signaling.
  • 基因功能参考文献：
    1. WT1 interference with Wnt signaling represents an important mode of its action relevant to the suppression of tumor growth and guidance of development. PMID: 19549856
  • 亚细胞定位：
    Nucleus. Cytoplasm. Nucleus speckle.
  • 蛋白家族：
    EGR C2H2-type zinc-finger protein family
  • 组织特异性：
    Expressed around the pronephric anlage and in the pronephros; expression is restricted to the splanchnic mesoderm (the site where the glomus forms) from tailbud stages, and the glomus of early tadpoles. Not expressed in the pronephric tubules or pronephri
  • 数据库链接：

    KEGG: xla:373588

    UniGene: Xl.172