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  4. Recombinant Xenopus tropicalis Nodal homolog 3-B (nodal3-B)

Recombinant Xenopus tropicalis Nodal homolog 3-B (nodal3-B)

  • 中文名称：
    热带爪蟾nodal3-B重组蛋白
  • 货号：
    CSB-YP773657XBF
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    热带爪蟾nodal3-B重组蛋白
  • 货号：
    CSB-EP773657XBF
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    热带爪蟾nodal3-B重组蛋白
  • 货号：
    CSB-EP773657XBF-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    热带爪蟾nodal3-B重组蛋白
  • 货号：
    CSB-BP773657XBF
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    热带爪蟾nodal3-B重组蛋白
  • 货号：
    CSB-MP773657XBF
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    nodal3-B
  • Uniprot No.：
  • 别名：
    nodal3-B; nr3-B; Nodal homolog 3-B; Nodal-related protein 3-B; Xtnr3-B
  • 种属：
    Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    275-401
  • 氨基酸序列
    NKKEKT RMDVGTTPPK PVEEIKPKCR KVDMFVDFQK IGWGSWIVYP KAYNAYRCES ACAVPLNETD DATNYSYIKS LLPLSDTERR ECPSCVPVKM RSMSMLYYEN EEFILRHHEE MIVEECGFKD I
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Exhibits mesoderm-dorsalizing activity and neural-inducing activity, but lacks mesoderm-inducing activity. Regulates the expression of specific mesodermal and neural genes. Induces convergent extension movements at the embryonic midline by activating the fgf signaling pathway to induce t/bra expression in the organizer region. Acts with wnt11 to induce Spemann organizer cells and induce axis formation. The unprocessed protein antagonizes bmp-signaling.
  • 基因功能参考文献：
    1. Data indicate that enhancers are in an active conformation prior to Nodal signaling and are established independently of Nodal signaling. PMID: 25205067
    2. Data show taht NR3B confers proton sensitivity also to receptors containing NR1b variants - possibly via disturbing the "proton shield" of NR1b splice variants. PMID: 19348678
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    TGF-beta family
  • 组织特异性：
    Expressed in the dorsal marginal region of late blastula, becoming restricted to the Spemann organizer at the early gastrula stage.
  • 数据库链接：

    KEGG: xtr:394458

    UniGene: Str.7735