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  4. Recombinant Arabidopsis thaliana Protein TOO MANY MOUTHS (TMM)

Recombinant Arabidopsis thaliana Protein TOO MANY MOUTHS (TMM)

  • 中文名称：
    拟南芥TMM重组蛋白
  • 货号：
    CSB-CF879826DOA
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    TMM
  • Uniprot No.：
  • 别名：
    TMM; RLP17; At1g80080; F18B13.16; Protein TOO MANY MOUTHS; Receptor-like protein 17; AtRLP17
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    24-496
  • 氨基酸序列
    FTVITSDSTAPSALIDGPQTGFTMTNDGARTEPDEQDAVYDIMRATGNDWAAAIPDVCRG RWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDPQRSYVSESLTRLKHLKALFFYRCL GRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSF NRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRN RVTGPIPESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAF KGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLN DNSLTGPVPFERDTVWRMRRKLRLYNNAGLCVNRDSDLDDAFGSKSGSTVRLCDAETSRP APSGTVQHLSREEDGALPDGATDVSSTSKSLGFSYLSAFFLVFPNFIFMLISS
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Promotes cell fate progression in stomatal development. In leaves, needed to correctly orient spacing divisions, to limit the number of asymmetric divisions in neighbor cells, and to promote the asymmetric (amplifying) divisions of meristemoids. In stems, promotes the conversion of meristemoids into guard mother cells (GMC). Positively regulates CAPRICE (CPC) expression in differentiating stomaless-forming cell files. Forms constitutive complexes with ERECTA and ERL1 involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN. Modulates the activity of the ligand-receptor pairs EPF2-ERECTA and EPF1-ERL1 in stomatal development. Functions in a combinatorial specific manner with the ERECTA-family (ERf) receptor kinases in the regulation of the immune response.
  • 基因功能参考文献：
    1. Data demonstrate that TMM dictates the specificity of ERECTA family for the perception of different epidermal patterning factor peptides (EPfs), thus functioning as a specificity switch for the regulation of the activities of ERfs. PMID: 28536146
    2. Brassinosteroid organ-specific effects on stomatal production might coordinate with the TMM organ-specific actions. PMID: 25234048
    3. TMM was involved in Abscisic Acid (ABA) signaling transduction. Overexpression of TMM resulted in the reduction of leaf trichomes and their branches. PMID: 24553751
    4. CHAL and the EPFs both act through ER family receptors to repress stomatal production, but are subject to opposite regulation by TMM PMID: 20056678
    5. TMM interacts with other proteins to modulate precursor cell fate and progression in an organ and domain-specific manner. PMID: 18979118

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  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    RLP family
  • 组织特异性：
    In epidermal cells of developing shoots and leaves, but not in roots. Expressed in the stomatal cell lineage in the developing epidermis. Accumulates strongly in meristemoid mother cells (MMC) and meristemoids, somewhat less in meristemoid sister cells (s
  • 数据库链接：

    KEGG: ath:AT1G80080

    STRING: 3702.AT1G80080.1

    UniGene: At.33989