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Recombinant Calcitonin receptor-like protein 1 (pdfr-1)

  • 中文名称：
    秀丽隐杆线虫pdfr-1重组蛋白
  • 货号：
    CSB-CF600242CXY
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    pdfr-1
  • Uniprot No.：
  • 别名：
    pdfr-1; seb-1; C13B9.4; Calcitonin receptor-like protein 1; Pigment dispersing factor neuropeptide receptor homolog 1
  • 种属：
    Caenorhabditis elegans
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-546
  • 氨基酸序列
    MADATSPFNVSILDNSTKLSEMVESGWNVLASTSVQAFNEAMDVLEESYPLCKKMLDHNN LFPERDPNDTRIWCNATYDTVLCWPPTPANSSVTLQCPHMKGLDPNKNITKDCHVSGVWS GRNAGEMGPTLPGWTNFTMCYTDEVIYIMQNLNNESLTIAQEVARNARKLEFVGLGLSLV SLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGK TINTMPIVCEGMFFFLEYFKTVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIAGYGIP LVHTMLWLLVVLIKKDFKVERCLGSYYLEPEFWILDGPRMAELVINLFFICNVIRVLYSK VRESNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNIMVFAVWTYTASFTYMY QGLMVASIYCFTNKEVNHVLKTFYARYRLLHKSQNELRRGSRSVASHYAAKNGTANASAP QTNNADEFGKLSPFPSRSKKGSDDSTTKLMKDAVMEEEKNANNNGYGSAGEMTPLREGSN RSTKSP
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    G-protein coupled receptor for PDF neuropeptides. Activated by peptides PDF-1 and PDF-2 but to a lesser extent with isoform c. Isoforms a and b are thought to act through the G-alpha(s) type of G proteins to elevate cAMP levels whereas isoform c inhibits cAMP levels through the G-alpha(i/o) type of G proteins. Involved in locomotion; more specifically mate searching behavior independent of nutritional status. Might have a role in touch sensitivity.
  • 基因功能参考文献：
    1. The PDFR-1 pathway functions in non-sex-specific neurons to produce a male-specific, goal-oriented exploratory behavior. PMID: 23143519
    2. The pdfr-1 mutant phenocopies the defective locomotor behavior of the pdf-1 mutant. PMID: 22579613
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 2 family
  • 组织特异性：
    Expression was observed in the mechanosensory neuron pairs PLM, ALM, FLP, OLQD, and OLQV, the chemosensory neurons PHA, PHB, RMEV, the ring motor neurons RMED, and the pharyngeal interneuron pair I1. In both hermaphrodites and males at the L4 stage expres
  • 数据库链接：

    STRING: 6239.C13B9.4a.1

    UniGene: Cel.22708