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  4. Recombinant Danio rerio Estradiol 17-beta-dehydrogenase 12-A (hsd17b12a)

Recombinant Danio rerio Estradiol 17-beta-dehydrogenase 12-A (hsd17b12a)

  • 中文名称：
    斑马鱼hsd17b12a重组蛋白
  • 货号：
    CSB-CF747402DIL
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    hsd17b12a
  • Uniprot No.：
  • 别名：
    hsd17b12a; zgc:55589; Very-long-chain 3-oxoacyl-CoA reductase-A; 17-beta-hydroxysteroid dehydrogenase 12-A; 17-beta-HSD 12-A; zf3.1; zfHSD17B12A; 3-ketoacyl-CoA reductase; KAR; Estradiol 17-beta-dehydrogenase 12-A
  • 种属：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-319
  • 氨基酸序列
    MESFNVVETLQPAERALFWVGALITASLALYVVYKTITGFRIWVLGNGDLLSPKLGKWAV VTGATDGIGKSYAEELARRGFSMMLISRSQEKLDDVAKSLESTYKVETKTIAVDFSQIDV YPKIEKGLAGLEIGILVNNVGISYSYPEFFLHIPDLENFITTMINVNITSVCQMTRLVLP RMEARAKGVILNISSASGMFPVPLLTIYSSTKAFVDFFSRGLQTEYKCKGIIIQSVLPFF VATKMTKIRKPTLDKPTPERYVAAELNTVGLQDQTNGYFPHAVMGWVTTILAPIDLVLNL GLRMNKAQRGGYLRRRKLR
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family, 17-beta-HSD 3 subfamily
  • 数据库链接：

    KEGG: dre:327417

    STRING: 7955.ENSDARP00000014003

    UniGene: Dr.29406