Recombinant Dog Gap junction alpha-5 protein (GJA5)
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中文名称:熟悉的犬GJA5重组蛋白
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货号:CSB-CF009448DO
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规格:
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来源:in vitro E.coli expression system
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其他:
产品详情
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基因名:GJA5
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Uniprot No.:
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别名:GJA5; Gap junction alpha-5 protein; Connexin-40; Cx40
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种属:Canis familiaris (Dog) (Canis lupus familiaris)
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蛋白长度:Full Length of Mature Protein
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表达区域:2-358
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氨基酸序列GDWSFLGEFLEEVHKHSTVIGKVWLTVLFIFRMLVLGTAAESSWGDEQADFQCDTMQPGC GNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEARGAG SYEYPVAEKAELSCWEEVNGRIVLQGTLLNTYVCSILIRTTMEVAFIVGQYLLYGIFLDT LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLFLSLAELYHLGWKKLRQRFVKS GQGMAECQLPGPSAGIVQNCTPPPDFNQCLENGPGGKFFNPFSNKMASQQNTDNLATEQV QGQEPIPGEGFIHIRYAQKPEVPNGASPGHRLPHGYQSDKRRLSKASSKARSDDLSV
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. -
蛋白标签:N-terminal 10xHis-tagged
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产品提供形式:Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
缓冲液:Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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储存条件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保质期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事项:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet & COA:Please contact us to get it.
相关产品
靶点详情
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功能:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
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基因功能参考文献:
- Increased myocardial fibrosis is positively correlated with upregulation of myocardial Cx 40 protein expression in left atrium in rapid atrial paced canines. PMID: 21426757
- Altered transmural gradient of Cx40/43 contributes to vulnerability of sterile pericarditis model to induction/maintenance of atrial arrhythmias. PMID: 17434983
- three heterozygous base changes (C384G, C402T, C837T) in the dogs screened and determined them to be synonymous mutations. These mutations, however, have recently been found in an unrelated group of normal dogs. PMID: 17939028
- During atrial fibrillation, the calpain system of the myocardial sleeve tissue is activated and may hydrolyze Cx40 protein PMID: 18577882
- Report changes in connexin expression and the atrial fibrillation substrate in congestive heart failure. PMID: 19875729
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亚细胞定位:Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
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蛋白家族:Connexin family, Alpha-type (group II) subfamily
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数据库链接:
KEGG: cfa:483155
STRING: 9615.ENSCAFP00000016302
UniGene: Cfa.13792
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