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  4. Recombinant Drosophila melanogaster Gustatory receptor 68a (Gr68a)

Recombinant Drosophila melanogaster Gustatory receptor 68a (Gr68a)

  • 中文名称：
    黑腹果蝇Gr68a重组蛋白
  • 货号：
    CSB-CF893802DLU
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Gr68a
  • Uniprot No.：
  • 别名：
    Gr68a; GR68D.1; CG7303; Gustatory receptor 68a
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-389
  • 氨基酸序列
    MKIYQDIYPISKPSQIFAILPFYSGDVDDGFRFGGLGRWYGRLVALIILIGSLTLGEDVL FASKEYRLVASAQGDTEEINRTIETLLCIISYTMVVLSSVQNASRHFRTLHDIAKIDEYL LANGFRETYSCRNLTILVTSAAGGVLAVAFYYIHYRSGIGAKRQIILLLIYFLQLLYSTL LALYLRTLMMNLAQRIGFLNQKLDTFNLQDCGHMENWRELSNLIEVLCKFRYITENINCV AGVSLLFYFGFSFYTVTNQSYLAFATLTAGSLSSKTEVADTIGLSCIWVLAETITMIVIC SACDGLASEVNGTAQILARIYGKSKQFQNLIDKFLTKSIKQDLQFTAYGFFSIDNSTLFK IFSAVTTYLVILIQFKQLEDSKVEDISQA
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Dsx-dependent essential component of pheromone-driven courtship behavior. Recognizes a female pheromone involved in the second step (tapping step) of the courtship display which is essential for efficient execution of the entire courtship sequence and timely mating. Required for detection of the male sex pheromone CH503 which is transferred from males to females during mating and inhibits courtship behavior by other males. Gr68a-expressing neurons in the male foreleg relay signals to the suboesophageal zone (SEZ) and courtship suppression is mediated by the release of the neuropeptide tachykinin from a cluster of 8-10 neurons in the SEZ.
  • 基因功能参考文献：
    1. This study constructed a receptor-to-sensillum map of the legs and a receptor-to-neuron map. PMID: 24849350
    2. GR68a protein recognizes a female pheromone(s) involved in the second step of the courtship display, which is essential for efficient execution of the entire courtship and timely mating. PMID: 12971900
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Insect chemoreceptor superfamily, Gustatory receptor (GR) family, Gr21a subfamily
  • 组织特异性：
    Expressed in chemosensory neurons of about 20 male-specific gustatory bristles in the forelegs. No expression is seen in the mechanosensory neurons. In larvae, expressed in the ventral pharyngeal sense organ.
  • 数据库链接：

    KEGG: dme:Dmel_CG7303

    STRING: 7227.FBpp0075849

    UniGene: Dm.27850