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  4. Recombinant Human Protein FAM176A (FAM176A)

Recombinant Human Protein FAM176A (FAM176A)

  • 中文名称：
    人EVA1A重组蛋白
  • 货号：
    CSB-CF862042HU
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    EVA1A
  • Uniprot No.：
  • 别名：
    EVA1A; FAM176A; TMEM166; SP24; Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-152
  • 氨基酸序列
    MRLPLSHSPEHVEMALLSNILAAYSFVSENPERAALYFVSGVCIGLVLTLAALVIRISCH TDCRRRPGKKFLQDRESSSDSSDSEDGSEDTVSDLSVRRHRRFERTLNKNVFTSAEELER AQRLEERERIIREIWMNGQPEVPGTRSLNRYY
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.
  • 基因功能参考文献：
    1. Low EVA1A expression is associated with glioblastoma. PMID: 28185834
    2. The adenovirus-mediated increase of FAM176A inhibited the growth of the tumor cells. PMID: 24257118
    3. TMEM166 expression was widely down-regulated in the cancer tissues. PMID: 22495369
    4. Low TMEM166 mRNA and protein expression is associated with esophageal squamous cell carcinoma. PMID: 23098460
    5. TMEM166 is a novel regulator involved in both autophagy and apoptosis. PMID: 17492404

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  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein.
  • 蛋白家族：
    EVA1 family
  • 组织特异性：
    Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.
  • 数据库链接：

    HGNC: 25816

    KEGG: hsa:84141

    STRING: 9606.ENSP00000233712

    UniGene: Hs.302346