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  4. Recombinant Inward rectifier potassium channel irk-1 (irk-1)

Recombinant Inward rectifier potassium channel irk-1 (irk-1)

  • 中文名称：
    秀丽隐杆线虫irk-1重组蛋白
  • 货号：
    CSB-CF346354CXY
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    irk-1
  • Uniprot No.：
  • 别名：
    irk-1; irk-4; R03E9.4; Inward rectifier potassium channel irk-1
  • 种属：
    Caenorhabditis elegans
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-505
  • 氨基酸序列
    MLLDTNTITFPFFVNGLFRFQDSANSLVIQTKMPSCAHSISALSFLESIRTLAFTARRNS SPLYRKSTKKLKKSRLVGKNGICNVYNTNVPKKDRQYLRDIFTTMIDVKWRWMLMLFASA FVLSWSIFGTTYYLIALVHGDLSLPTPVNHTACVMNLDSVYSSFLFAVETHHTIGYGHRY ITTECYLAGAIVCLQAICALLLQSFMVGIVFAKMARPKKRAETIIFSDKAVICLRDGQLC FLCRVGDMRNTHLVEAHVRLQFITDRETNEGEIEPLHQFEMKVGPSIADDDRLFLVWPTT LCHVIDSRSPLYNYNQQTLMSAQFEIIVLLEGIVESTGMTAQAKTSYLPSEVLWGHRFRK LVTYQRSNGSYQIDYDLFHSTYPVRTPAMSPAEFYSSKPNLKDYYCHDSHEHKLEDNRSS DSTPLPSPSPYSYPSTPLNHFQSSSNSPVFSNNHSKFNTEAVTCEAGMLCPPTIVVQCPS TCASPNHMRRTRNQMDKSRTRYSIA
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Required for modulation of the activity of the hermaphrodite-specific neurons (HSNs) by the G-protein coupled neuropeptide receptor egl-6 which in turn controls egg-laying behavior.
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Detected in perikarya and neurites of HSNs.
  • 蛋白家族：
    Inward rectifier-type potassium channel (TC 1.A.2.1) family
  • 组织特异性：
    Expressed in neurons in the head and tail with no expression detected in non-neuronal cells in these regions. Also detected in the egg-laying system of adult hermaphordites with strong expression in the HSN motor neurons and weak expression in vulval musc
  • 数据库链接：

    KEGG: cel:CELE_R03E9.4

    STRING: 6239.R03E9.4

    UniGene: Cel.39258