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  4. Recombinant Mouse Integral membrane protein 2A (Itm2a)

Recombinant Mouse Integral membrane protein 2A (Itm2a)

In Stock
  • 货号：
    CSB-CF011903MO
  • 规格：
    ￥9720
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    Itm2a
  • Uniprot No.：
  • 别名：
    Itm2a; E25; Itm2; Integral membrane protein 2A; Protein E25
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length
  • 来源：
    in vitro E.coli expression system
  • 分子量：
    31.2 kDa
  • 表达区域：
    1-263aa
  • 氨基酸序列
    MVKIAFNTPTAVQKEEARQDVEALVSRTVRAQILTGKELRVVPQEKDGSSGRCMLTLLGLSFILAGLIVGGACIYKYFMPKSTIYHGEMCFFDSEDPVNSIPGGEPYFLPVTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVMTPKNLVELFGKLASGKYLPHTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLRRRDLLLGFNKRAIDKCWKIRHFPNEFIVETKICQE
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Itm2a knockdown is sufficient to rescue the inhibitory effects of lamin A WT and R482W mutant overexpression on 3T3-L1 differentiation. PMID: 28872940
    2. Itm2a possesses diverse functional properties as evidenced by differential expression during odontogenesis. PMID: 25079563
    3. Itm2a is a target gene of GATA-3 that plays a minimal role in regulating the development and function of T cells PMID: 24831988
    4. Itm2a is not only expressed in adult muscle fibres but also in the satellite cells responsible for regeneration. PMID: 23650549
    5. Results support the involvement of Itm2a in the early stages of chondrogenesis in vitro. PMID: 15325075
    6. Both Itm2a and Itm2c were not detected in the epididymis and vas deferens during sexual maturation. PMID: 17873332

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  • 亚细胞定位：
    Membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    ITM2 family
  • 组织特异性：
    Expressed in mandibular condyles, in bone and in hair follicles. Strong expression in osteogenic tissues, such as neonatal calvaria, paws, tail and skin.
  • 数据库链接：

    KEGG: mmu:16431

    STRING: 10090.ENSMUSP00000033591

    UniGene: Mm.193