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  4. Recombinant Mouse Mas-related G-protein coupled receptor member B4 (Mrgprb4)

Recombinant Mouse Mas-related G-protein coupled receptor member B4 (Mrgprb4)

  • 中文名称：
    小鼠Mrgprb4重组蛋白
  • 货号：
    CSB-CF838710MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Mrgprb4
  • Uniprot No.：
  • 别名：
    Mrgprb4; Mrgb4; Mas-related G-protein coupled receptor member B4
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-321
  • 氨基酸序列
    MGTTTLAWNINNTAENGSYTEMFSCITKFNTLNFLTVIIAVVGLAGNGIVLWLLAFHLHR NAFSVYVLNLAGADFLYLFTQVVHSLECVLQLDNNSFYILLIVTMFAYLAGLCMIAAISA ERCLSVMWPIWYHCQRPRHTSAIMCALVWVSSLLLSLVVGLGCGFLFSYYDYYFCITLNF ITAAFLIVLSVVLSVSSLALLVKIVWGSHRIPVTRFFVTIALTVVVFIYFGMPFGICWFL LSRIMEFDSIFFNNVYEIIEFLSCVNSCANPIIYFLVGSIRQHRLRWQSLKLLLQRAMQD TPEEESGERGPSQRSGELETV
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain.
  • 基因功能参考文献：
    1. Study shows that a mechanically activated ion channel is functionally expressed in the Mas-related G-protein coupled receptor B4 (MrgprB4) positive sensory neurons, which detect stroking of hairy skin in mice. These results raise the possibility that the MrgprB4+ neurons directly detect the stroking-like stimuli of hairy skin. PMID: 28545921
    2. The Mas-related G protein-coupled receptor B4 marks a rare subpopulation of unmyelinated, nonpeptidergic sensory fibers that exclusively innervate hairy skin. PMID: 17618277
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family, Mas subfamily
  • 数据库链接：

    KEGG: mmu:233230

    STRING: 10090.ENSMUSP00000091952

    UniGene: Mm.377250