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Recombinant Mouse Mpv17-like protein (Mpv17l)

  • 中文名称：
    小鼠Mpv17l重组蛋白
  • 货号：
    CSB-CF860825MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Mpv17l
  • Uniprot No.：
  • 别名：
    Mpv17l; Mpv17-like protein; M-LP
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-194
  • 氨基酸序列
    MASWWRAFPQAARRYPWPTNVLLYAGLFSAGDALQQRLRGGPADWRQTRRVATLAVTFHG NFNYVWLRLLERALPGRAPRTVLAKVLCDQTVGGPIALSAFYVGMSVLQGKDDIFLDLKQ KFWNTYKSGLMYWPFVQLTNFSLVPVHWRTAYTGLCAFLWATFLCFSQQSGDGTLQSIFI FLRRKEASDKSPEK
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Isoform 1 and isoform 3 participate in reactive oxygen species metabolism by up- or down-regulation of the genes of antioxidant enzymes.
  • 基因功能参考文献：
    1. participates in reactive oxygen species metabolism PMID: 12471025
    2. In mice, M-LPs is expressed exclusively in kidneys after 6 weeks. Transfection with M-LPS up-regulates SOD2 and down-regulates cellular glutathione peroxidase (Gpx1) and plasma glutathione peroxidase (Gpx3) gene expression PMID: 15541722
    3. identify Mpv17l as a unique interacting protein and regulator of HtrA2 protease mediating antioxidant and antiapoptotic function in mitochondria PMID: 18772386
  • 亚细胞定位：
    [Isoform 1]: Peroxisome membrane; Multi-pass membrane protein.; [Isoform 3]: Cytoplasm.
  • 蛋白家族：
    Peroxisomal membrane protein PXMP2/4 family
  • 组织特异性：
    Isoform 1 and isoform 3 are expressed in the kidney (at protein level). Isoform 1 is expressed in the kidney, spleen, heart, brain, lung and liver. Isoform 3 is expressed in the kidney. Isoform 1 and isoform 3 expression increase during development, reach
  • 数据库链接：

    KEGG: mmu:93734

    STRING: 10090.ENSMUSP00000023360

    UniGene: Mm.76554