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Recombinant Mouse Neurensin-1 (Nrsn1)

  • 中文名称：
    小鼠Nrsn1重组蛋白
  • 货号：
    CSB-CF016093MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Nrsn1
  • Uniprot No.：
  • 别名：
    Nrsn1; Vmp; Neurensin-1; Neuro-p24; Vesicular membrane protein of 24 kDa; Vesicular membrane protein p24
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-196
  • 氨基酸序列
    MTSCSNTCGSRRAQADTEGGYQQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSS VFWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFMVVDTHAVKYNGALDTCKLAG AVLFCIGGTSMAGCLLMSVFAKSYSKEEKFLQQKFKERIADIKAHTQPITKAPGPGDTKI PVTLSRVQNVQPLSAT
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension.
  • 基因功能参考文献：
    1. In behavioral analyses, overexpressing Nrsn1, one of the newly identified genes undergoing rapid translational repression, or activating ESR1 in the hippocampus impaired memory formation. PMID: 26430118
    2. Neurensin-2 was expressed in small vesicles including lysosomes in the perinuclear region. And was found in cell bodies. PMID: 16527258
    3. Neurensin-1 plays a role in the fiber extension of the retinal neurons, and indicate that the developing retina is a suitable experimental model for the analysis of Neurensin function, both in vivo and in vitro. PMID: 16696124
    4. The results of this study indicate that Nrsn1 plays an active role in axonal regeneration as well as in embryonic development. PMID: 17566649
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein. Cell projection, neuron projection.
  • 蛋白家族：
    VMP family
  • 组织特异性：
    Expressed predominantly in brain. Also weakly expressed in lung and spleen. In brain, expressed strongly in nerve fibers of the cerebral cortex, anterior cerebral nuclei, hypothalamus, amygdaloid complex, brain stem of the metaencephalon and medulla oblon
  • 数据库链接：

    KEGG: mmu:22360

    UniGene: Mm.4766