Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 跨膜蛋白
  4. Recombinant Mouse Probable G-protein coupled receptor 97 (Gpr97)

Recombinant Mouse Probable G-protein coupled receptor 97 (Gpr97)

  • 货号：
    CSB-CF823150MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
  • Uniprot No.：
  • 别名：
    Adgrg3; Gpr97; Adhesion G protein-coupled receptor G3; G-protein coupled receptor 97
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    19-542
  • 氨基酸序列
    EETTEEPRNVCRRLQEGHEYDTFDLNDTAQCFTKCGQSEHSPCDVGNLQRYWLNYESYLL ENSMETVDMPFVKALIQNISTDVSEDLLYSLMLSQIPRQVMQGEDEPADGVRLPKSLFGA LPGNRSAVRLAITVLDIGAGNVFKGPKLLEDKGSSVLNNRMVGLSVGQMHATGLSEPVEI TFSHERQPPNVILTCVFWDMAKGDWDSHGCSTVPGDGRTVCRCDHLTFFALLLRPILDLA TAQTLTRISQAGSAVSMIFLAFTMVLYVAFRFSLQRFKSEDAPKIHMALSISLFLLNLTF LINVGSSSQGPPASCWVRAAIFHYFLLCVFTWMGLEAFHLYLLAIRVFNTYFGHYFLKLS LLAWGLPVLVVIGAGSSNSYGVYTIRDQENRTSLELCWFQKEPALYATVHGYFLVTFLFG AVVLALVAWKIFTLPSVTAGKGQGPTWKSVLTVLGLSSLVGMTWGLAVLTPLGLSTIYVF TLLNSLQGLFIFCWFIILYFPTQSTTASSSGTARLDQAHSVSQE
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Orphan receptor that regulates migration of lymphatic endothelial cells via the small GTPases RhoA and CDC42. Regulates B-cell development. Seems to signal through G-alpha(q)-proteins.
  • 基因功能参考文献：
    1. Results show that G protein-coupled receptor 97 protein (Gpr97) plays an important role in the development of experimental autoimmune encephalomyelitis (EAE) and may have a therapeutic potential for the treatment of central nervous system (CNS) autoimmunity. PMID: 29860267
    2. Our findings imply that Gpr97 might not be required for the development of airway inflammation in OVA-induced allergic asthma in mice. PMID: 26132811
    3. The GPR92 is expressed in the majority of T1R1-positive taste cells. PMID: 23436159
    4. Gpr97 deficiency results in an extensive reduction in B220(+) lymphocytes in mice. PMID: 24113187
    5. a possible role of GPR97 in lymphatic remodeling PMID: 24178298

    显示更多

    收起更多

  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 组织特异性：
    Specifically expressed in intestinal lymphatic endothelium.
  • 数据库链接：

    KEGG: mmu:54672

    STRING: 10090.ENSMUSP00000051079

    UniGene: Mm.27995