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  4. Recombinant Mouse Tyrosine-protein kinase STYK1 (Styk1)

Recombinant Mouse Tyrosine-protein kinase STYK1 (Styk1)

  • 中文名称：
    小鼠Styk1重组蛋白
  • 货号：
    CSB-CF760834MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Styk1
  • Uniprot No.：
  • 别名：
    Styk1; Nok; Tyrosine-protein kinase STYK1; Novel oncogene with kinase domain; mNOK; Serine/threonine/tyrosine kinase 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-429
  • 氨基酸序列
    MGEKGHLSRVLLECSLSDKLCVVREKQYEVIIVPALLVGGFLILLAIILWLFIRGQRSQR QSPGPRGTASVPASRGRSQEAAGHGEKVLLPLKETSVEGFLRAATPRLAKLQVPREQLLE VLEQIHSGSCGTLYHATMTTKDHPKPKSVVLKALEDPVGLQEVQDFIGRIQFYQYLGKHK NLVQLEGCCTERLPLYMMLEDVVPGDLLSFLWTCRRDVMTMDGLLYDLTEKQIYHIGKQI LLALEFLQEKHLFHGDVAARNILIQSDLTPKLCHLGLAYEVHAHGAISSARSSTIPLKWL APERLLLRPASIRGDIWSFGILLYEMVTLGAPPYPEVPPTSILQYLQRKKIMKRPSSCSH AMYNIMKCCWRWSEDSRPLLGQLLQRLEAASRSADDKAVLQVPELVVPELYADVAGIRAE SISYSFSVL
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines including NIH 3T3 fibroblasts and on athymic nude mice. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways.
  • 基因功能参考文献：
    1. Point mutations at either Y327 or Y356 dramatically blocked cellular transformation by NOK as examined by colony formation and cellular DNA synthesis. PMID: 16322230
  • 亚细胞定位：
    Membrane; Single-pass membrane protein.
  • 蛋白家族：
    Protein kinase superfamily, Tyr protein kinase family
  • 组织特异性：
    Highly expressed in colon and small intestine. Weakly or not expressed in spleen, skeletal muscle, liver, kidney, heart and brain. Expressed in transformed kidney cell lines (COS-1 and HEK293T).
  • 数据库链接：

    KEGG: mmu:243659

    STRING: 10090.ENSMUSP00000044098

    UniGene: Mm.20114