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  4. Recombinant Mouse Vesicle-associated membrane protein 4 (Vamp4)

Recombinant Mouse Vesicle-associated membrane protein 4 (Vamp4)

  • 货号：
    CSB-CF025783MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Vamp4
  • Uniprot No.：
  • 别名：
    Vamp4; Vesicle-associated membrane protein 4; VAMP-4
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-141
  • 氨基酸序列
    MPPKFKRHLNDDDVTGSVKSERRNLLEDDSDEEEDFFLRGPSGPRFGPRNDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALAAAILLLMIIILIVVKFRT
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.
  • 基因功能参考文献：
    1. Cholesterol modulates Vamp4 distribution in insulin granule membranes. PMID: 22889194
    2. The cytoplasmic domain of this protein is responsible for its correct subcellular targeting, the N-terminal extension contains a dominant autonomous targeting signal for the trans-golgi network PMID: 12682051
  • 亚细胞定位：
    Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein.
  • 蛋白家族：
    Synaptobrevin family
  • 数据库链接：

    KEGG: mmu:53330

    STRING: 10090.ENSMUSP00000051544

    UniGene: Mm.10699