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  4. Recombinant Rat CDGSH iron-sulfur domain-containing protein 1 (Cisd1)

Recombinant Rat CDGSH iron-sulfur domain-containing protein 1 (Cisd1)

  • 货号：
    CSB-CF005442RA
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Cisd1
  • Uniprot No.：
  • 别名：
    Cisd1; CDGSH iron-sulfur domain-containing protein 1; MitoNEET
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-108
  • 氨基酸序列
    GLSSDSPVRVEWIAAVTFAAGTAALGYLAYKKFYAKESRTKAMVNLQIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHIKHNEETGDNVGPLIIKKKET
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions.
  • 基因功能参考文献：
    1. MicroRNA-127 targets mitoNEET, which inhibits neurite outgrowth, induces cell apoptosis and contributes to physiological dysfunction after spinal cord transection PMID: 27748416
    2. mito- NEET is an important iron-containing protein involved in the control of maximal mitochondrial respiratory rates [mitoNEET] PMID: 17376863
    3. mitoNEET is located in mitochondrial fraction of rat brain, liver and skeletal muscle. PMID: 14570702
    4. describes methods for isolating mitochondrial membrane fractions that are enriched in mitoNEET, generating constructs for the expression of recombinant mitoNEET protein and analyzing the 2Fe-2S cluster of mitoNEET in vitro PMID: 19348892
  • 亚细胞定位：
    Mitochondrion outer membrane; Single-pass type III membrane protein.
  • 蛋白家族：
    CISD protein family
  • 数据库链接：

    KEGG: rno:294362

    STRING: 10116.ENSRNOP00000000749

    UniGene: Rn.1164