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  4. Recombinant Rat Probable G-protein coupled receptor 88 (Gpr88)

Recombinant Rat Probable G-protein coupled receptor 88 (Gpr88)

  • 货号：
    CSB-CF872148RA
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
  • Uniprot No.：
  • 别名：
    Gpr88; Strg; Probable G-protein coupled receptor 88; Striatum-specific G-protein coupled receptor
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-384
  • 氨基酸序列
    MTNSSSTSTSTTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFR KLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPAGSAEPPGDWDSGGGSYRLLRGGLL GLGLTVSLLSHCLVALNRYLLITRAPATYQVLYQRRHTAGMLALSWALALGLVLLLPPWA PKPGAEPPQVHYPALLAAGALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGC AAAAAAFPAAPHAPGAGGAAHPAQPQPLPAALQPRRAQRRLSGLSVLLLCCVFLLATQPL VWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGVGDAAAA AAAATAVPAMSQAQLGTRAAGQHW
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function.
  • 基因功能参考文献：
    1. Therefore, we conclude that GPR88 and GPR124 receptors may be involved in the development or maintenance of high blood pressure. PMID: 28678544
    2. In the developing cortex, GPR88 shifts on the day of birth to the nuclei of neurons in layers V to II. PMID: 26918661
    3. Results suggest a role for Gpr88 in the regulation of cognitive and motor functions, and support its relevance to the pathophysiology and treatment of schizophrenia and other disorders involving dysfunction of the accumbens-striatal complex PMID: 25155879
    4. GPR88 is confined to striatal medium spiny neurons and indicate that L-DOPA-mediated behavioural effects in hemiparkinsonian rats may involve normalization of striatal GPR88 levels PMID: 19656174
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Cytoplasm. Nucleus.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 组织特异性：
    Expressed predominantly in the striatum. Expressed also in olfactory tubercle, nucleus accumbens, amygdala, and neocortex. Spinal cord, pons, and medulla expression remains discrete. Also expressed in peripheral tissues, including adrenal cortex (E16-E21)
  • 数据库链接：

    KEGG: rno:64443

    STRING: 10116.ENSRNOP00000038233

    UniGene: Rn.59513