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  4. Recombinant Saccharomyces cerevisiae ADIPOR-like receptor IZH2 (IZH2)

Recombinant Saccharomyces cerevisiae ADIPOR-like receptor IZH2 (IZH2)

  • 中文名称：
    酿酒酵母IZH2重组蛋白
  • 货号：
    CSB-CF622480SVG
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    IZH2
  • Uniprot No.：
  • 别名：
    IZH2; PHO36; YOL002C; UND327; ADIPOR-like receptor IZH2; Phosphate metabolism protein 36
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-317
  • 氨基酸序列
    MSTLLERTKSVQELKKRAAGKTSANPAEVAKAKKVLRRLYSWDEIPEWQRDNDFILHGYV KETSSFIETFKSLFYLHNESVNIYSHLIPALGFFTVLLLDKSTIKVFATTTWLDHMVIDL FYSGAFACLILSSSFHCLKSHSLRIATLGNKLDYLGICILIVTSMVSILYYGYFEKFSLF CLFALITVSFGIACSIVSLKDKFRKREWRPYRAGLFVCFGLSSIIPIFSGLYCYSFSEIW TQIQLFWVLLGGVLYIIGAVLYGMRFPEKICPGKFDIWGHSHQLFHFLVVIAALCHLRGL LNSYELVHIKMENGIVS
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable receptor, which is involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation.
  • 基因功能参考文献：
    1. Studied yeast Izh2 protein and zinc ion homeostasis and in the regulation of lipid and phosphate metabolism. PMID: 26067383
    2. Double disruption of the EOS1 and IZH2 genes yielded a slow-growth phenotype, suggesting that the two proteins are involved in related cellular processes. PMID: 20146743
    3. Data show that the protein encoded by ORE20/PHO36 (YOL002c) is an osmotin binding plasma membrane protein that is required for full sensitivity to osmotin. PMID: 15664187
    4. Data show that overproduction of Izh2p prevents the iron-dependent induction of the Fet3p component of the high-affinity iron-uptake system and is deleterious for growth in iron-limited medium. PMID: 17553578
    5. Izh2p negatively regulates functionally divergent genes through a CCCTC promoter motif. PMID: 18625204
    6. Izh2p produces sphingoid bases, bioactive lipids which probably function as the second messenger responsible for the repressive effect of Izh2p on iron-uptake gene FET3. PMID: 19066337

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  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ADIPOR family
  • 数据库链接：

    KEGG: sce:YOL002C

    STRING: 4932.YOL002C