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  4. Recombinant Saccharomyces cerevisiae Protein ARV1 (ARV1)

Recombinant Saccharomyces cerevisiae Protein ARV1 (ARV1)

  • 货号：
    CSB-CF002161SVG
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    ARV1
  • Uniprot No.：
  • 别名：
    ARV1; YLR242C; Protein ARV1
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-321
  • 氨基酸序列
    MICITCMRPVDSLYTVYSNDHIQLTDCPYCQETVDKYVEIDNVLLFIDLLLLKAGAYRHL VFNALELHLSKYPKRKALNDCQCLRDYTQALLFNVKNWFCKYDRLNRLWLLLLSFEIYLT WVTEESKYIYYLNRNNNDGKLIMLSKKLPESFKWDSAIMRNTITSKVFTWSPPIQYLYFA SYCILDVSLFHTFTQYFILKKLHWKHYSVSSKDVISYTILLSYGAKIFPILMLIWPYDTL ISMSIIKWVANLYIIESLKIVTNLSYWNIIKIFISVSLLRYFMVKPILIVFVAKFNFSVI KNLIHQEFILLLQKSGTYLLL
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes. Regulates also the sphingolipid metabolism. Required for growth during anaerobiosis and sterol uptake.
  • 基因功能参考文献：
    1. The most liposensitive yeast strain arose due to deletion of the "ARE2 required for viability" (ARV1) gene, encoding an evolutionarily conserved, potential lipid transporter that localizes to the endoplasmic reticulum membrane. PMID: 24273168
    2. Arv1 deficiency affects structure and homeostasis of plasma and ER membranes, and does not affect sterol transport between ER and plasma membrane. PMID: 23668914
    3. In the presence of drug, S. cerevisiae cells lacking Arv1 are unable to induce ERG gene expression, have an altered pleiotrophic drug response, and are defective in multi-drug resistance efflux pump expression PMID: 22142782
    4. Yeast Arv1p is an important protein required for the delivery of an early gycosylphosphatidylinositol (GPI)intermediate, GlcN-acylPI, to the first mannosyltransferase of GPI synthesis in the endoplasmic reticulum lumen. PMID: 18287539
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ARV1 family
  • 数据库链接：

    KEGG: sce:YLR242C

    STRING: 4932.YLR242C