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  4. Recombinant Saccharomyces cerevisiae UPF0041 protein FMP37 (FMP37)

Recombinant Saccharomyces cerevisiae UPF0041 protein FMP37 (FMP37)

  • 中文名称：
    酿酒酵母MPC1重组蛋白
  • 货号：
    CSB-CF345656SVG
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    MPC1
  • Uniprot No.：
  • 别名：
    MPC1; FMP37; YGL080W; Mitochondrial pyruvate carrier 1; MPC1; Protein FMP37
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-130
  • 氨基酸序列
    MSQPVQRAAARSFLQKYINKETLKYIFTTHFWGPVSNFGIPIAAIYDLKKDPTLISGPMT FALVTYSGVFMKYALSVSPKNYLLFGCHLINETAQLAQGYRFLKYTYFTTDEEKKALDKE WKEKEKTGKQ
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Mediates the uptake of pyruvate into mitochondria.
  • 基因功能参考文献：
    1. while expression of Mpc1 is not dependent on the carbon source, expression of Mpc2 and Mpc3 is specific to fermentative or respiratory conditions, respectively. This gives rise to two alternative carrier complexes PMID: 25672363
    2. Mpc1 (YGL080W )and Mpc2 (YHR162W) associate to form a complex in the inner mitochondrial membrane; loss of Mpc1 results in defective mitochondrial pyruvate uptake; data demonstrate that Mpc1 and Mpc2 form an essential part of the mitochondrial pyruvate carrier PMID: 22628558
    3. study concludes that the mitochondrial pyruvate carrier is composed of Mpc1(Ygl080w) and either Mpc2 (Yhr162w) or Mpc3 (Ygr243w); members of the MPC family were found in the inner mitochondrial membrane; mutants lacking MPC proteins showed severe defects in mitochondrial pyruvate uptake PMID: 22628554
  • 亚细胞定位：
    Mitochondrion. Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family
  • 数据库链接：

    KEGG: sce:YGL080W

    STRING: 4932.YGL080W