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TARS2 Antibody

  • 中文名称：
    TARS2兔多克隆抗体
  • 货号：
    CSB-PA023132LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA023132LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA023132LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TARS2 Polyclonal antibody
  • Uniprot No.：
    Q9BW92
  • 基因名：
  • 别名：
    TARS2 antibody; TARSL1 antibody; Threonine--tRNA ligase antibody; mitochondrial antibody; EC 6.1.1.3 antibody; Threonyl-tRNA synthetase antibody; ThrRS antibody; Threonyl-tRNA synthetase-like 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Threonine--tRNA ligase, mitochondrial protein (369-718AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TARS2 Antibody (CSB-PA023132LA01HU)，的标记方式是Non-conjugated。对于TARS2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023132LB01HU TARS2 Antibody, HRP conjugated ELISA
    FITC CSB-PA023132LC01HU TARS2 Antibody, FITC conjugated
    Biotin CSB-PA023132LD01HU TARS2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain.
  • 基因功能参考文献：
    1. Identification of a TARS2 splicing variant in several human cell lines, which encodes a hmtThrRS derivative lacking a peptide covering a portion of both the editing and the aminoacylation domains. PMID: 26811336
    2. TARS2 mutations caused fatal mitochondrial encephalomyopathy in two siblings. PMID: 24827421
  • 相关疾病：
    Combined oxidative phosphorylation deficiency 21 (COXPD21)
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Class-II aminoacyl-tRNA synthetase family
  • 数据库链接：

    HGNC: 30740

    OMIM: 612805

    KEGG: hsa:80222

    STRING: 9606.ENSP00000358060

    UniGene: Hs.288974