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IL24

IL24,即白细胞介素24,它是一种由T细胞、B细胞、巨噬细胞和树突状细胞等多种免疫细胞产生的细胞因子。IL24属于IL-10细胞因子家族,通过与特异性受体复合体结合,如IL20RA/IL20RB或IL20RB/IL22RA1,激活下游的JAK-STAT信号通路,进而调控免疫反应和细胞增殖。其作用机制包括促进肿瘤细胞凋亡、抑制肿瘤血管生成,以及增强对放化疗的敏感性。在生物学意义上,IL24具有抗肿瘤活性,其表达水平与多种肿瘤的低恶性和转移性相关,是肿瘤治疗和免疫调节的潜在靶点。

热销产品

IL24 Antibody (CSB-PA613378LA01HU)

验证数据

CSB-PA613378LA01HU

IHC image of CSB-PA613378LA01HU diluted at 1:1400 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA613378LA01HU

IHC image of CSB-PA613378LA01HU diluted at 1:1400 and staining in paraffin-embedded human melanoma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IL24 Antibodies

IL24 for Homo sapiens (Human)

IL24 Proteins

IL24 Proteins for Homo sapiens (Human)

IL24 Proteins for Mus musculus (Mouse)

IL24 Proteins for Rattus norvegicus (Rat)

IL24 ELISA Kit

IL24 ELISA Kit for Homo sapiens (Human)