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AR

雄激素受体(Androgen Receptor,AR)是一个核内受体,在非活性状态下结合于分子伴侣(chaperone)。它包括N端的转录激活区域、DNA结合区域以及C端的激活功能区域。 他主要包括的功能如下:转录调控、性别特征发育、细胞增殖等。 雄激素受体与前列腺癌等多种疾病有关。雄激素受体与多个信号通路相关联,如PI3K/AKT、MAPK等信号通路,影响细胞增殖和生长。 总的来说,雄激素受体作为一个重要的转录因子,在性别特征形成、细胞增殖和多种疾病的发生中都发挥着关键作用。对其功能的深入了解有助于理解疾病的发生机制,并可能提供新的治疗靶点。

热销产品

Recombinant Human Androgen receptor (AR), partial

验证数据

SDS-PAGE
CSB-EP001975HU SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.


AR Antibodies

AR for Homo sapiens (Human)

AR Proteins

AR Proteins for Homo sapiens (Human)

AR Proteins for Mus musculus (Mouse)

AR Proteins for Oryctolagus cuniculus (Rabbit)

AR Proteins for Eulemur fulvus collaris (Collared brown lemur) (Eulemur collaris)

AR Proteins for Papio hamadryas (Hamadryas baboon)

AR Proteins for Pan troglodytes (Chimpanzee)

AR Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

AR Proteins for Rattus norvegicus (Rat)

AR Proteins for Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)

AR Proteins for Macaca mulatta (Rhesus macaque)

AR Proteins for Crocuta crocuta (Spotted hyena)

AR Proteins for Sus scrofa (Pig)

AR Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

AR Proteins for Bombyx mori (Silk moth)

AR ELISA Kit

AR ELISA Kit for Rattus norvegicus (Rat)