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ASIP

Agouti-signaling protein is a protein in humans that is encoded by ASIP gene. Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.

ASIP Antibodies

ASIP for Homo sapiens (Human)

ASIP Proteins

ASIP Proteins for Mus musculus (Mouse)

ASIP Proteins for Homo sapiens (Human)

ASIP Proteins for Macaca mulatta (Rhesus macaque)

ASIP Proteins for Vulpes vulpes (Red fox)

ASIP Proteins for Macaca sylvanus (Barbary macaque)

ASIP Proteins for Macaca nigra (Celebes black macaque) (Crested black macaque)

ASIP Proteins for Trachypithecus auratus (Javan langur)

ASIP Proteins for Callithrix jacchus (White-tufted-ear marmoset)

ASIP Proteins for Callimico goeldii (Goeldi's marmoset)

ASIP Proteins for Papio anubis (Olive baboon)

ASIP Proteins for Cebuella pygmaea (Pygmy marmoset) (Callithrix pygmaea)

ASIP Proteins for Macaca nemestrina (Pig-tailed macaque)

ASIP Proteins for Callithrix geoffroyi (Geoffroy's marmoset)

ASIP Proteins for Leontopithecus chrysomelas (Golden-headed lion tamarin)

ASIP Proteins for Trachypithecus francoisi (Francois's leaf monkey) (Presbytis francoisi)

ASIP Proteins for Leontopithecus rosalia (Golden lion tamarin)

ASIP Proteins for Macaca nigrescens (Gorontalo macaque) (Macaca nigra nigrescens)

ASIP Proteins for Macaca arctoides (Stump-tailed macaque)

ASIP Proteins for Macaca cyclopis (Taiwan macaque)

ASIP Proteins for Macaca silenus (Lion-tailed macaque)

ASIP Proteins for Macaca hecki (Heck's macaque)

ASIP Proteins for Macaca fuscata fuscata (Japanese macaque)

ASIP Proteins for Macaca assamensis (Assam macaque) (Assamese macaque)

ASIP Proteins for Macaca maura (Moor macaque)

ASIP Proteins for Macaca sinica (Toque macaque) (Toque monkey)

ASIP Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

ASIP Proteins for Gorilla gorilla gorilla (Lowland gorilla)

ASIP Proteins for Colobus polykomos (Western black-and-white colobus monkey)

ASIP Proteins for Pongo pygmaeus (Bornean orangutan)

ASIP Proteins for Macaca radiata (Bonnet macaque)

ASIP Proteins for Erythrocebus patas (Red guenon) (Cercopithecus patas)

ASIP Proteins for Semnopithecus entellus (Hanuman langur) (Presbytis entellus)

ASIP Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)

ASIP Proteins for Cercopithecus mitis (Blue monkey)

ASIP Proteins for Pan troglodytes (Chimpanzee)

ASIP Proteins for Trachypithecus cristatus (Silvered leaf-monkey) (Presbytis cristata)

ASIP Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

ASIP Proteins for Bos taurus (Bovine)

ASIP Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

ASIP Proteins for Sus scrofa (Pig)

ASIP Proteins for Felis catus (Cat) (Felis silvestris catus)

ASIP Proteins for Equus caballus (Horse)

ASIP Proteins for Rattus norvegicus (Rat)