C1qc
C1QC，即Complement C1q Subcomponent C，是构成血清补体系统C1复合体的关键组分之一。C1QC与C1QA和C1QB链协同工作，与C1r和C1s两种酶前体结合，形成C1复合体，该复合体是激活补体级联反应的起点。C1QC由6条相同的多肽链组成，包含N端胶原样区域和C端球形结构域，后者负责识别免疫复合物。C1QC的作用机制涉及其球形头部与免疫复合物的结合，激活C1r和C1s，启动补体级联反应，导致病原体的溶解和免疫细胞的活化。生物学意义上，C1QC对于病原体的识别和清除、免疫应答的调节、细胞凋亡的促进以及细胞信号传导等方面发挥着重要作用。C1QC的异常表达或功能失调与多种自身免疫和炎症性疾病相关，使其成为治疗这些疾病的潜在靶点。
热销产品
C1QC Antibody (CSB-PA003641LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA003641LA01HU at dilution of 1:100
C1qc Antibodies
C1qc for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA050279 | C1QC Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA003641LA01HU | C1QC Antibody | Human | ELISA, IHC |
| CSB-PA003641LB01HU | C1QC Antibody, HRP conjugated | Human | ELISA |
| CSB-PA003641LC01HU | C1QC Antibody, FITC conjugated | Human | |
| CSB-PA003641LD01HU | C1QC Antibody, Biotin conjugated | Human | ELISA |
C1qc Proteins
C1qc Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003641MO1 CSB-EP003641MO1 CSB-BP003641MO1 CSB-MP003641MO1 CSB-EP003641MO1-B |
Recombinant Mouse Complement C1q subcomponent subunit C (C1qc), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
C1qc Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003641RA CSB-EP003641RA CSB-BP003641RA CSB-MP003641RA CSB-EP003641RA-B |
Recombinant Rat Complement C1q subcomponent subunit C (C1qc) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
C1qc Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003641HU CSB-EP003641HU CSB-BP003641HU CSB-MP003641HU CSB-EP003641HU-B |
Recombinant Human Complement C1q subcomponent subunit C (C1QC) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
