CCL11
CCL11，即C-C motif chemokine ligand 11，也被称作Eotaxin-1，是一种小型诱导性细胞因子，属于C-C基序趋化因子家族成员之一。它在多种免疫细胞的迁移和活化中发挥关键作用，尤其是对嗜酸性粒细胞、嗜碱性粒细胞和Th2淋巴细胞具有强烈的化学吸引作用。CCL11通过与趋化因子受体如CCR2、CCR3和CCR5结合来发挥作用，其中CCR3是介导CCL11生物学效应的主要受体。CCL11参与了多种生理和病理过程，包括哮喘时嗜酸性粒细胞的归巢、肿瘤微环境中免疫细胞的招募以及在衰老和神经退行性疾病中的潜在作用。研究表明，CCL11在老年人中表达上调，并与某些年龄相关疾病的发展相关联。此外，CCL11的表达还与肿瘤微环境的免疫调节有关，可能影响肿瘤的发展和患者的预后。
热销产品
CCL11 Antibody (CSB-PA004775ESR2HU)
验证数据
Western blot
All lanes: CCL11 antibody at 5μg/ml + Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 11 kDa
Observed band size: 11 kDa
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004775ESR2HU at dilution of 1:100
Rat Eotaxin 1 (Eotaxin 1/CCL11/ECF)ELISA Kit (CSB-E07319r)
验证数据
货号：CSB-E07319r
规格：96T/48T
灵敏度：3.9 pg/ml
检测范围：15.6 pg/ml -1000 pg/ml
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CCL11 Antibodies
CCL11 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA004775GA01HU | CCL11 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004775ESR2HU | CCL11 Antibody | Human | ELISA, WB, IHC |
| CSB-PA005780 | CCL11 Antibody | Human,Mouse,Rat | WB, ELISA |
CCL11 Proteins
CCL11 Proteins for Cavia porcellus (Guinea pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004775GU CSB-EP004775GU CSB-BP004775GU CSB-MP004775GU CSB-EP004775GU-B |
Recombinant Guinea pig Eotaxin (CCL11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCL11 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004775RA CSB-EP004775RA CSB-BP004775RA CSB-MP004775RA CSB-EP004775RA-B |
Recombinant Rat Eotaxin (Ccl11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001561RA | Recombinant Rat Eotaxin protein (Ccl11) | E.Coli |
CCL11 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004775MO CSB-EP004775MO CSB-BP004775MO CSB-MP004775MO CSB-EP004775MO-B |
Recombinant Mouse Eotaxin (Ccl11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001291MO | Recombinant Mouse Eotaxin protein (Ccl11) | E.Coli |
CCL11 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004775HU CSB-BP004775HU CSB-MP004775HU CSB-EP004775HU-B |
Recombinant Human Eotaxin (CCL11) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP000901HU | Recombinant Human Eotaxin protein (CCL11) | E.Coli |
| CSB-EP004775HU | Recombinant Human Eotaxin (CCL11) | E.coli |
CCL11 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP850742MOW CSB-EP850742MOW CSB-BP850742MOW CSB-MP850742MOW CSB-EP850742MOW-B |
Recombinant Macaca mulatta Eotaxin (CCL11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001041MOW | Recombinant Rhesus Macaque Eotaxin protein (CCL11) | E.Coli |
CCL11 Proteins for Equus caballus (Horse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP890591HO CSB-EP890591HO CSB-BP890591HO CSB-MP890591HO CSB-EP890591HO-B |
Recombinant Horse Eotaxin (CCL11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCL11 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP890592BO CSB-EP890592BO CSB-BP890592BO CSB-MP890592BO CSB-EP890592BO-B |
Recombinant Bovine Eotaxin (CCL11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCL11 ELISA Kit
CCL11 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04533h | Human eosinophil chemotactic factor,ECF ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 7.8 pg/mL |
CCL11 ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E07319r | Rat Eotaxin 1 (Eotaxin 1/CCL11/ECF)ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/ml |
