CD147
CD147,(也称为Basigin或EMMPRIN),是一种跨膜蛋白,属于免疫球蛋白超家族,其结构含有一个细胞外N端和一个胞内C端。它有一个Ig-like(免疫球蛋白样)细胞外结构域,可与其他蛋白质发生相互作用。CD147广泛表达在许多细胞类型中,包括免疫细胞、白血球、红血球、神经细胞、胶质细胞、肿瘤细胞等。它在细胞间黏附和迁移过程中发挥重要作用,并参与多种生物学过程,如细胞的增殖、侵袭、转移以及免疫细胞的活化和炎症反应等。 在肿瘤学中,CD147被认为是一种肿瘤相关标志物,因为它在多种肿瘤细胞表面的表达水平明显升高,与肿瘤细胞的侵袭和转移有关。CD147还参与调节肿瘤微环境中的细胞间相互作用,对肿瘤的生长和进展具有一定的影响。此外,CD147在免疫调节和感染过程中也发挥着重要作用。它与病原体感染、炎症反应和免疫细胞的活化和迁移等过程密切相关。是疾病治疗和新药开发的潜在靶点。
热销产品
● Recombinant Human Basigin(BSG),partial (Active)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized CD147 at 2 μg/ml can bind Anti-CD147 recombinant Antibody, the EC50 is 21.95-33.12 ng/ml.
● CD147 Recombinant Monoclonal Antibody CSB-RA002831A0HU
验证数据
Positive WB detected in: HepG2 whole cell lysate, ntera2 whole cell lysate, A549 whole cell lysate, U251 whole cell lysate
All lanes: CD147 antibody at 1:1000
Secondary
Goat polyclonal to mouse IgG at 1/50000 dilution
Predicted band size: 42, 29, 23, 19 KDa
Observed band size: 35, 50-60 KDa
CD147 Antibodies
CD147 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA11759A0Rb | BSG Antibody | Human | ELISA, WB, IHC |
CSB-PA11759C0Rb | BSG Antibody, FITC conjugated | Human | |
CSB-PA002831GA01HU | BSG Antibody | Human | ELISA,WB,IHC |
CSB-PA11759B0Rb | BSG Antibody, HRP conjugated | Human | ELISA |
CSB-PA11759D0Rb | BSG Antibody, Biotin conjugated | Human | ELISA |
CSB-PA002331 | BSG Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA005853 | BSG Antibody | Human | WB, ELISA |
CSB-PA993569 | BSG Antibody | Human | ELISA,IHC |
CSB-PA570608 | BSG Antibody | Human | ELISA,WB,IHC |
CSB-RA002831A0HU | CD147 Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IF, FC |
CD147 Proteins
CD147 Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP002831MO1 CSB-EP002831MO1 CSB-BP002831MO1 CSB-MP002831MO1 CSB-EP002831MO1-B |
Recombinant Mouse Basigin (Bsg), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF002831MO | Recombinant Mouse Basigin (Bsg) | in vitro E.coli expression system |
CD147 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP002831HU CSB-EP002831HU CSB-BP002831HU CSB-EP002831HU-B |
Recombinant Human Basigin (BSG), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
CSB-RP117574h | Recombinant Human Basigin (BSG), partial | E.coli |
CSB-CF002831HU | Recombinant Human Basigin (BSG) | in vitro E.coli expression system |
CSB-MP002831HU | Recombinant Human Basigin (BSG), partial | Mammalian cell |
CSB-MP002831HUf3 | Recombinant Human Basigin (BSG), partial | Mammalian cell |
CSB-MP002831HU1 | Recombinant Human Basigin (BSG), partial (Active) | Mammalian cell |
CD147 Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP002831RA1 CSB-EP002831RA1 CSB-BP002831RA1 CSB-MP002831RA1 CSB-EP002831RA1-B |
Recombinant Rat Basigin (Bsg), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF002831RA | Recombinant Rat Basigin (Bsg) | in vitro E.coli expression system |
CD147 Proteins for Oryctolagus cuniculus (Rabbit)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP631727RB CSB-EP631727RB CSB-BP631727RB CSB-MP631727RB CSB-EP631727RB-B |
Recombinant Rabbit Basigin (BSG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD147 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP857519DXU CSB-EP857519DXU CSB-BP857519DXU CSB-MP857519DXU CSB-EP857519DXU-B |
Recombinant Cricetulus griseus Basigin (BSG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD147 ELISA Kit
CD147 ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E12994h | Human Cluster of differentiation 147,CD147 Elisa Kit | serum, plasma | 3.12 pg/mL |