CEACAM6
CEACAM6（Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6），也被称为CD66c，属于Carcinoembryonic Antigen（CEA）家族，这是一组与癌症和胚胎发育相关的蛋白质。CEACAM6是一种单链糖蛋白，它包括一个细胞外结构域、一个跨膜域以及一个细胞内结构域。细胞外结构域包括一个或多个IgV结构域，用于细胞间粘附和相互作用。它通过与其他细胞表面的CEACAM蛋白相互作用，参与细胞-细胞粘附，从而在多种生理和病理过程中发挥作用，包括免疫应答、细胞迁移和肿瘤转移。此外，CEACAM6还可以与其他细胞信号分子相互作用，影响细胞的信号传导通路。CEACAM6已被考虑作为癌症标志物，可用于诊断和监测疾病进展。 此外，研究人员还在探索如何利用CEACAM6的特性来开发癌症治疗策略，如免疫治疗和靶向治疗。
更多CEACAM6相关文章请点击：CEA家族癌胚抗原细胞粘附分子，肿瘤新标志物或抗癌潜力靶点！
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验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CEACAM6 at 2 μg/mL can bind Human CEACAM8 (CSB-MP005168HU), the EC50 is 144.7-223.8 ng/mL.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CEACAM6 at 2 μg/mL can bind Anti- CEACAM5/CEACAM6 recombinant antibody (CSB-RA005165MA2HU), the EC50 is 0.9430-1.377 ng/mL.
CEACAM6 Antibodies
CEACAM6 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA999004 | CEACAM6 Antibody | Human | ELISA,IHC |
| CSB-PA832895 | CEACAM6 Antibody | Human | ELISA,IHC |
| CSB-PA005166LA01HU | CEACAM6 Antibody | Human | ELISA, IHC, IF |
CEACAM6 Proteins
CEACAM6 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP005166HU CSB-BP005166HU CSB-EP005166HU-B |
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP005166HU | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) | E.coli |
| CSB-MP005166HU | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) (Active) | Mammalian cell |
CEACAM6 ELISA Kit
CEACAM6 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL005166HU | Human Carcinoembryonic antigen-related cell adhesion molecule 6(CEACAM6) ELISA kit | serum, plasma, tissue homogenates | 0.33 ng/mL |
