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CFTR

CFTR,即囊性纤维化跨膜传导调节器,是一种广泛表达在上皮细胞膜上的ATP门控离子通道,属于ATP结合盒式转运体超家族。CFTR的作用机制涉及到两个核苷酸结合结构域(NBDs)的二聚化,以及随后的构象变化,这些变化受ATP水解的支配,从而调节氯离子的传导。CFTR的功能异常会导致囊性纤维化,这是一种常见的遗传性疾病,其特征是体内多个组织器官的水盐平衡失调,引起营养不良、肝脏疾病、反复的细菌感染、慢性炎症及呼吸衰竭等症状。在生物学意义上,CFTR对维持上皮细胞膜上的盐和液体平衡至关重要,其正常功能对于防止呼吸道和消化道的黏液堵塞、维持肺功能和消化健康具有重要作用。

热销产品

Human Cystic fibrosis transmembrane conductance regulator(CFTR) ELISA kit (CSB-EL005292HU)

验证数据

CSB-EL005292HU 标准曲线

货号:CSB-EL005292HU

规格:96T/48T

灵敏度:7 pg/mL

检测范围:28 pg/mL-1800 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CFTR Antibodies

CFTR for Homo sapiens (Human)

CFTR Proteins

CFTR Proteins for Ovis aries (Sheep)

CFTR Proteins for Oryctolagus cuniculus (Rabbit)

CFTR Proteins for Homo sapiens (Human)

CFTR Proteins for Mus musculus (Mouse)

CFTR Proteins for Bos taurus (Bovine)

CFTR Proteins for Rattus norvegicus (Rat)

CFTR Proteins for Squalus acanthias (Spiny dogfish)

CFTR Proteins for Xenopus laevis (African clawed frog)

CFTR Proteins for Loxodonta africana (African elephant)

CFTR Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

CFTR Proteins for Gorilla gorilla gorilla (Lowland gorilla)

CFTR Proteins for Pongo abelii (Sumatran orangutan)

CFTR Proteins for Rhinolophus ferrumequinum (Greater horseshoe bat)

CFTR Proteins for Equus caballus (Horse)

CFTR Proteins for Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)

CFTR Proteins for Callicebus moloch (Dusky titi monkey)

CFTR Proteins for Microcebus murinus (Lesser mouse lemur)

CFTR Proteins for Carollia perspicillata (Seba's short-tailed bat)

CFTR Proteins for Pan troglodytes (Chimpanzee)

CFTR Proteins for Callithrix jacchus (White-tufted-ear marmoset)

CFTR Proteins for Didelphis marsupialis virginiana (North American opossum)

CFTR Proteins for Trichosurus vulpecula (Brush-tailed possum)

CFTR Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

CFTR Proteins for Macaca fuscata fuscata (Japanese macaque)

CFTR Proteins for Sus scrofa (Pig)

CFTR Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

CFTR Proteins for Papio anubis (Olive baboon)

CFTR Proteins for Macaca nemestrina (Pig-tailed macaque)

CFTR ELISA Kit

CFTR ELISA Kit for Homo sapiens (Human)