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Csf2

CSF2,即集落刺激因子2,别名粒细胞-巨噬细胞集落刺激因子(Granulocyte-Macrophage Colony-Stimulating Factor,GM-CSF)。它是一种由多种细胞类型分泌的细胞因子,如巨噬细胞、T细胞、肥大细胞、自然杀伤细胞、内皮细胞和成纤维细胞。CSF2的主要作用是促进髓系造血祖细胞的增殖和分化,特别是对粒细胞和巨噬细胞系列的影响尤为显著。它通过与其特异性受体结合,激活JAK/STAT信号通路,促进细胞增殖、分化和成熟。CSF2在生物学上的意义非常重要,它对免疫系统的发育和功能至关重要。CSF2参与调节炎症反应、促进组织修复和伤口愈合,并且在某些疾病的发病机制中也发挥作用,如类风湿性关节炎。此外,CSF2的异常表达或功能失调与多种疾病有关,包括某些类型的癌症和自身免疫疾病。在肿瘤微环境中,CSF2也可能影响肿瘤细胞的行为,包括增殖、侵袭和转移。

热销产品

Recombinant Human Granulocyte-macrophage colony-stimulating factor (CSF2) (CSB-MP006045HU)

验证数据

CSB-MP006045HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Csf2 Antibodies

Csf2 for Homo sapiens (Human)

Csf2 Proteins

Csf2 Proteins for Bos taurus (Bovine)

Csf2 Proteins for Ovis aries (Sheep)

Csf2 Proteins for Rattus norvegicus (Rat)

Csf2 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

Csf2 Proteins for Mus musculus (Mouse)

Csf2 Proteins for Felis catus (Cat) (Felis silvestris catus)

Csf2 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

Csf2 Proteins for Sus scrofa (Pig)

Csf2 Proteins for Cavia porcellus (Guinea pig)

Csf2 Proteins for Homo sapiens (Human)

Csf2 ELISA Kit

Csf2 ELISA Kit for Homo sapiens (Human)

Csf2 ELISA Kit for Mus musculus (Mouse)

Csf2 ELISA Kit for Rattus norvegicus (Rat)