FSHR
卵泡刺激素受体（FSHR）属于G蛋白偶联受体超家族中的糖蛋白亚家族成员，由胞外区、胞内区及跨膜区3部分组成。FSHR通过与其配体——卵泡刺激素（FSH）结合参与信号转导。
FSH是垂体分泌的一种糖蛋白激素，主要作用是促进和维持正常的性腺发育和生殖功能。FSH可以通过与FSHR结合来刺激女性卵巢中卵泡的发育，促进男性睾丸的精子发生。FSH主要通过FSHR介导的腺苷酸环化酶-环磷酸腺苷（cAMP）途径发挥作用。已证实FSH通过特异性结合FSHR胞外区的富含亮氨酸重复序列来激活稳定态受体。活化的FSHR刺激位于细胞膜内膜的偶联鸟苷结合蛋白（Gs蛋白）传递信息。被活化的Gs蛋白激活腺苷酸化话梅促成胞质内第二信使cAMP生产，cAMP再激活蛋白激酶A，促进蛋白磷酸化，实现生理效应。
FSHR的表达被认为是性腺特异性的。长期以来，人们认为FSHR的表达仅限于卵巢的颗粒细胞和睾丸的支持细胞，但后来发现FSHR在胎盘、子宫、前列腺、骨组织和卵巢上皮细胞以及卵巢癌。此外，最近有研究发现FSHR在许多肿瘤血管表面选择性表达，并且发现FSHR的表达与原发性肾细胞癌的肿瘤转移密切相关。FSHR的表达水平在女性卵泡发育的不同阶段也不同。
热销产品
Recombinant Human Follicle-stimulating hormone receptor(FSHR),partial（CSB-MP009021HUd9）
验证数据
High Purity Validated by SDS-PAGE
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
FSHR Antibodies
FSHR for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA002586 | FSHR Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA008484 | FSHR Antibody | Human | WB, IF, ELISA |
| CSB-PA924165 | FSHR Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA288553 | FSHR Antibody | Human,Mouse,Rat | ELISA,IHC |
FSHR Proteins
FSHR Proteins for Gallus gallus (Chicken)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009021CH1 CSB-EP009021CH1 CSB-BP009021CH1 CSB-MP009021CH1 CSB-EP009021CH1-B |
Recombinant Chicken Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009021CH | Recombinant Chicken Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009021RA1 CSB-EP009021RA1 CSB-BP009021RA1 CSB-MP009021RA1 CSB-EP009021RA1-B |
Recombinant Rat Follicle-stimulating hormone receptor (Fshr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009021RA | Recombinant Rat Follicle-stimulating hormone receptor (Fshr) | in vitro E.coli expression system |
FSHR Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009021HU CSB-EP009021HU-B |
Recombinant Human Follicle-stimulating hormone receptor (FSHR), partial | Yeast In Vivo Biotinylation in E.coli |
| CSB-EP009021HU | Recombinant Human Follicle-stimulating hormone receptor (FSHR), partial | E.coli |
| CSB-BP009021HU | Recombinant Human Follicle-stimulating hormone receptor (FSHR), partial | Baculovirus |
| CSB-MP009021HU | Recombinant Human Follicle-stimulating hormone receptor (FSHR), partial | Mammalian cell |
| CSB-MP009021HUd9 | Recombinant Human Follicle-stimulating hormone receptor (FSHR), partial | Mammalian cell |
FSHR Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009021MO1 CSB-EP009021MO1 CSB-BP009021MO1 CSB-MP009021MO1 CSB-EP009021MO1-B |
Recombinant Mouse Follicle-stimulating hormone receptor (Fshr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009021MO | Recombinant Mouse Follicle-stimulating hormone receptor (Fshr) | in vitro E.coli expression system |
FSHR Proteins for Ovis aries (Sheep)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009021SH1 CSB-EP009021SH1 CSB-BP009021SH1 CSB-MP009021SH1 CSB-EP009021SH1-B |
Recombinant Sheep Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009021SH | Recombinant Sheep Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009021BO1 CSB-EP009021BO1 CSB-BP009021BO1 CSB-MP009021BO1 CSB-EP009021BO1-B |
Recombinant Bovine Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009021BO | Recombinant Bovine Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Equus caballus (Horse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009021HO1 CSB-EP009021HO1 CSB-BP009021HO1 CSB-MP009021HO1 CSB-EP009021HO1-B |
Recombinant Horse Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009021HO | Recombinant Horse Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009021PI1 CSB-EP009021PI1 CSB-BP009021PI1 CSB-MP009021PI1 CSB-EP009021PI1-B |
Recombinant Pig Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009021PI | Recombinant Pig Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009021MOV1 CSB-EP009021MOV1 CSB-BP009021MOV1 CSB-MP009021MOV1 CSB-EP009021MOV1-B |
Recombinant Macaca fascicularis Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009021MOV | Recombinant Macaca fascicularis Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Felis catus (Cat) (Felis silvestris catus)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP702060CA1 CSB-EP702060CA1 CSB-BP702060CA1 CSB-MP702060CA1 CSB-EP702060CA1-B |
Recombinant Cat Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF702060CA | Recombinant Cat Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Macropus eugenii (Tammar wallaby)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP754488MPE1 CSB-EP754488MPE1 CSB-BP754488MPE1 CSB-MP754488MPE1 CSB-EP754488MPE1-B |
Recombinant Macropus eugenii Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF754488MPE | Recombinant Macropus eugenii Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Mesocricetus auratus (Golden hamster)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP757700MRG1 CSB-EP757700MRG1 CSB-BP757700MRG1 CSB-MP757700MRG1 CSB-EP757700MRG1-B |
Recombinant Mesocricetus auratus Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF757700MRG | Recombinant Mesocricetus auratus Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Cairina moschata (Muscovy duck)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP773819CAG1 CSB-EP773819CAG1 CSB-BP773819CAG1 CSB-MP773819CAG1 CSB-EP773819CAG1-B |
Recombinant Cairina moschata Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF773819CAG | Recombinant Cairina moschata Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Equus asinus (Donkey)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP842510DK1 CSB-EP842510DK1 CSB-BP842510DK1 CSB-MP842510DK1 CSB-EP842510DK1-B |
Recombinant Donkey Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF842510DK | Recombinant Donkey Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
FSHR Proteins for Cavia porcellus (Guinea pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP851270GU1 CSB-EP851270GU1 CSB-BP851270GU1 CSB-MP851270GU1 CSB-EP851270GU1-B |
Recombinant Guinea pig Follicle-stimulating hormone receptor (FSHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF851270GU | Recombinant Guinea pig Follicle-stimulating hormone receptor (FSHR) | in vitro E.coli expression system |
