IDUA
IDUA(Iduronidase)是一种属于糖苷水解酶家族的溶酶体酶,其结构复杂,包含多个催化位点和底物结合位点,能够识别和分解硫酸艾杜糖醛酸,这是黏多糖代谢中的关键步骤。IDUA的主要功能是催化硫酸艾杜糖醛酸的水解,维持细胞外基质的稳态和正常生理功能。尽管IDUA不直接参与信号转导,但它在黏多糖代谢中的作用可能间接影响某些信号通路,如通过影响细胞表面的受体与配体相互作用以及细胞间相互作用来改变细胞对外部刺激的响应。IDUA的缺乏会导致黏多糖累积病,如粘多糖贮积症I型(Hurler综合征),这突显了IDUA在人体健康中的重要作用。
热销产品
IDUA Antibody (CSB-PA011000LA01HU)
验证数据
IHC image of CSB-PA011000LA01HU diluted at 1:300 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA011000LA01HU diluted at 1:300 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IDUA Antibodies
IDUA for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA011000GA01HU | IDUA Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA011000LA01HU | IDUA Antibody | Human | ELISA, IHC |
CSB-PA011000LB01HU | IDUA Antibody, HRP conjugated | Human | ELISA |
CSB-PA011000LC01HU | IDUA Antibody, FITC conjugated | Human | |
CSB-PA011000LD01HU | IDUA Antibody, Biotin conjugated | Human | ELISA |
IDUA Proteins
IDUA Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP011000HU | Recombinant Human Alpha-L-iduronidase (IDUA) | Yeast |
CSB-EP011000HU | Recombinant Human Alpha-L-iduronidase (IDUA) | E.coli |
CSB-BP011000HU CSB-MP011000HU CSB-EP011000HU-B |
Recombinant Human Alpha-L-iduronidase (IDUA) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IDUA ELISA Kit
IDUA ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E09455h | Human α-L-iduronidase,IDUA ELISA Kit | serum, plasma, cell lysates, tissue homogenates | 0.039 ng/mL |