IGFLR1
IGFR1是胰岛素样生长因子1受体，也称为IGF-1R。它是一种细胞表面受体，在细胞生长、增殖和存活中发挥重要作用。IGFR1通过胰岛素样生长因子1（IGF-1）和胰岛素样生长因子2（IGF-2）这两种肽类激素来激活。 当IGF-1或IGF-2与IGFR1结合时，会触发一个信号级联，促进细胞分裂、生长和分化。这个受体在发育过程中以及成年后的组织维护中都至关重要。然而，IGF-1R信号通路的失调可能与多种疾病相关，包括癌症。 在癌症研究中，IGFR1已被研究为癌症治疗的潜在靶点。抑制IGFR1的活性可以是减缓癌细胞生长和减少肿瘤进展的策略。了解IGFR1的结构和功能对于在肿瘤学领域开发有针对性的治疗方法至关重要。
热销产品
● Recombinant Human IGF-like family receptor 1(IGFLR1),partial (Active) CSB-MP862025HUd9
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IGFLR1 at 2 μg/ml can bind Human IGFL1 (CSB-MP764932HUh8), the EC50 is 4.640-5.722 ng/mL.
● Recombinant Human IGF-like family receptor 1(IGFLR1),partial (Active) CSB-MP862025HU
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IGFLR1 at 2 μg/ml can bind Human IGFL1 (CSB-MP764932HU), the EC50 is 32.33-47.52 ng/mL.
IGFLR1 Proteins
IGFLR1 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP023719BO1 CSB-EP023719BO1 CSB-BP023719BO1 CSB-MP023719BO1 CSB-EP023719BO1-B |
Recombinant Bovine IGF-like family receptor 1 (IGFLR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF023719BO | Recombinant Bovine IGF-like family receptor 1 (IGFLR1) | in vitro E.coli expression system |
IGFLR1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP663649MO CSB-BP663649MO CSB-EP663649MO-B |
Recombinant Mouse IGF-like family receptor 1 (Igflr1), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP663649MO | Recombinant Mouse IGF-like family receptor 1 (Igflr1), partial | E.coli |
| CSB-MP663649MO | Recombinant Mouse IGF-like family receptor 1 (Igflr1), partial | Mammalian cell |
| CSB-MP663649MOd7 | Recombinant Mouse IGF-like family receptor 1 (Igflr1), partial | Mammalian cell |
IGFLR1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP862025HU CSB-EP862025HU CSB-BP862025HU CSB-EP862025HU-B |
Recombinant Human IGF-like family receptor 1 (IGFLR1), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP862025HUd9 | Recombinant Human IGF-like family receptor 1 (IGFLR1), partial (Active) | Mammalian cell |
| CSB-MP862025HU | Recombinant Human IGF-like family receptor 1 (IGFLR1), partial (Active) | Mammalian cell |
