Lif

白血病抑制因子（LIF）属于IL-6超家族的细胞因子。LIF可在不同的细胞中表达，包括活化的T细胞、单核细胞、胶质细胞、肝脏成纤维细胞、骨髓基质细胞、胚胎干细胞、胸腺上皮细胞和许多其他细胞。LIF的作用是通过一个高亲和力的受体复合物介导的，该复合物由一个低亲和力的LIFRβ（也称为LIFR）和一个高亲和力的亚单位gp130组成，从而激活STAT、p21ras/MAP和PI-3信号途径。LIF作为具有多种生物功能的细胞因子，可参与骨髓性白血病细胞的造血分化，肾脏发育过程中间质向上皮的转化。在癌症中也有强大的功能，参与了肿瘤生长和进展的一些关键过程，包括免疫耐受、PNI、化疗和放射抗性、癌症干细胞样表型维持、EMT和TME发展。

Recombinant Human LIF 活性蛋白实验验证数据

High Purity Validated by SDS-PAGE

CSB-MP006254HU(F1) is detected by Mouse anti-6*His monoclonal antibody.

Excellent Bioactivity Validated by Functional ELISA

Measured by its binding ability in a functional ELISA. Immobilized human LIF at 2 μg/ml can bind human LIFR (CSB-MP012929HUi9), the EC₅₀ is 22.58-30.24 ng/ml.

Lif Antibody

Lif Protein

Lif ELISA Kit

Lif Antibodies

Lif for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA012928ESR2HU	LIF Antibody	Human	ELISA
CSB-PA004761	LIF Antibody	Human	WB, ELISA
CSB-PA198481	LIF Antibody	Human,Mouse,Rat	ELISA,IHC

Lif Proteins

Lif Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP012928HU CSB-EP012928HU CSB-BP012928HU CSB-EP012928HU-B	Recombinant Human Leukemia inhibitory factor (LIF)	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-AP002221HU	Recombinant Human Leukemia inhibitory factor protein (LIF)	E.Coli
CSB-AP004001HU	Recombinant Human Leukemia inhibitory factor (LIF) (Active)	E.coli
CSB-MP012928HUd9	Recombinant Human Leukemia inhibitory factor (LIF) (Active)	Mammalian cell

Lif Proteins for Rattus norvegicus (Rat)

产品货号	产品名称	来源
CSB-YP012928RA CSB-EP012928RA CSB-BP012928RA CSB-MP012928RA CSB-EP012928RA-B	Recombinant Rat Leukemia inhibitory factor (Lif)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Lif Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP012928MO CSB-EP012928MO CSB-BP012928MO CSB-MP012928MO CSB-EP012928MO-B	Recombinant Mouse Leukemia inhibitory factor (Lif)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Lif Proteins for Mustela vison (American mink) (Neovison vison)

产品货号	产品名称	来源
CSB-YP528926MVE CSB-EP528926MVE CSB-BP528926MVE CSB-MP528926MVE CSB-EP528926MVE-B	Recombinant Mustela vison Leukemia inhibitory factor (LIF)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Lif Proteins for Bos taurus (Bovine)

产品货号	产品名称	来源
CSB-YP637735BO CSB-EP637735BO CSB-BP637735BO CSB-MP637735BO CSB-EP637735BO-B	Recombinant Bovine Leukemia inhibitory factor (LIF)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli