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MYD88

Myeloid differentiation primary response protein MyD88is a protein in humans that is encoded by MYD88 gene. Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.

MYD88 Antibodies

MYD88 for Homo sapiens (Human)

MYD88 Proteins

MYD88 Proteins for Mus musculus (Mouse)

MYD88 Proteins for Sus scrofa (Pig)

MYD88 Proteins for Gallus gallus (Chicken)

MYD88 Proteins for Macaca mulatta (Rhesus macaque)

MYD88 Proteins for Ovis aries (Sheep)

MYD88 Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)

MYD88 Proteins for Salmo salar (Atlantic salmon)

MYD88 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

MYD88 Proteins for Gorilla gorilla gorilla (Lowland gorilla)

MYD88 Proteins for Pan troglodytes (Chimpanzee)

MYD88 Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)

MYD88 Proteins for Pongo pygmaeus (Bornean orangutan)

MYD88 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

MYD88 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

MYD88 Proteins for Bos taurus (Bovine)

MYD88 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

MYD88 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

MYD88 Proteins for Rattus norvegicus (Rat)

MYD88 Proteins for Homo sapiens (Human)

MYD88 Proteins for Homo sapiens (Human)

MYD88 ELISA Kit

MYD88 ELISA Kit for Homo sapiens (Human)

MYD88 ELISA Kit for Mus musculus (Mouse)