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MYL12A

MYL12A,也被称为肌球蛋白轻链12A,其编码的蛋白质是非肌节性肌球蛋白调节轻链。这种蛋白质在平滑肌和非肌肉细胞收缩过程中起到关键作用,其磷酸化状态可以影响肌动蛋白复合物的活性,从而调节肌肉收缩强度、细胞运动速度等。因此,MYL12A在肌肉收缩运动、细胞分裂等多种生命活动中发挥重要作用。 此外,近期研究发现,MYL12A在多种疾病中扮演重要角色。其磷酸化水平与心脏疾病(如心肌损伤、心肌肥厚)和癌症相关,因此,MYL12A有望作为心脏、肿瘤等多种疾病的研究潜力靶点,成为重要的生物学标志物。

热销产品

Recombinant Human Myosin regulatory light chain 12A (MYL12A) (Active)

验证数据

SDS
CSB-EP015307HUc7 SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
CSB-EP015307HUc7 ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human MYL12A at 2μg/mL can bind Anti-MYL9 recombinant antibody (CSB-RA015318MA1HU),the EC50 is 5.325-6.456 ng/mL.


MYL12A Proteins

MYL12A Proteins for Homo sapiens (Human)

MYL12A Proteins for Pongo abelii (Sumatran orangutan)