Mtor
MTOR,即哺乳动物雷帕霉素靶蛋白,别名哺乳动物靶蛋白、Rapamycin受体、FRAP等。它是一种多功能的丝氨酸/苏氨酸蛋白激酶,由人体细胞自身的基因编码。MTOR是雷帕霉素(mTOR)信号通路的关键调控因子,主要在细胞内参与调控蛋白质合成、细胞增殖、代谢和自噬等过程。MTOR的作用机制涉及到其作为两个不同的复合体mTORC1和mTORC2的催化亚基,这两个复合体在细胞内响应不同的营养和环境信号,调节不同的生物学过程。MTOR在生物学上的意义非常广泛,它参与了多种细胞生命活动的调控。作为细胞内营养和能量状态的主要感受器,MTOR通过整合多种信号,如氨基酸、生长因子和能量状态等,来调节细胞的生长和代谢。mTORC1的活性与细胞的蛋白质合成、自噬和细胞大小调控密切相关,而mTORC2则参与细胞的生存和细胞骨架的组织。MTOR信号通路的异常激活与多种疾病有关,包括癌症、糖尿病、心血管疾病和神经退行性疾病等,因此,MTOR抑制剂已成为治疗这些疾病的潜在药物。
热销产品
MTOR Antibody (CSB-PA008968HA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA008968HA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA008968HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Mtor Antibodies
Mtor for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA008968GA01HU | MTOR Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA271384 | Phospho-MTOR (Ser2448) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA208208 | MTOR (Ab-2448) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA054657 | MTOR (Ab-2481) Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA000576 | Phospho-MTOR (S2448) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA000652 | Phospho-MTOR (T2446) Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA003333 | MTOR Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA008479 | Phospho-MTOR (S2481) Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
CSB-PA008481 | MTOR Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA876444 | MTOR Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA273227 | MTOR Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA008968HA01HU | MTOR Antibody | Human | ELISA, IHC, IF |
CSB-PA008968HB01HU | MTOR Antibody, HRP conjugated | Human | ELISA |
CSB-PA008968HC01HU | MTOR Antibody, FITC conjugated | Human | |
CSB-PA008968HD01HU | MTOR Antibody, Biotin conjugated | Human | ELISA |
CSB-RA008968A2481phHU | Phospho-MTOR (S2481) Recombinant Monoclonal Antibody | Human | ELISA, WB, IF |
CSB-RA008968A2448phHU | Phospho-MTOR (S2448) Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IF |
Mtor Proteins
Mtor Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP008968HU CSB-BP008968HU CSB-MP008968HU CSB-EP008968HU-B |
Recombinant Human Serine/threonine-protein kinase mTOR (MTOR), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP008968HU | Recombinant Human Serine/threonine-protein kinase mTOR (MTOR), partial | E.coli |
Mtor Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP008968RA CSB-EP008968RA CSB-BP008968RA CSB-MP008968RA CSB-EP008968RA-B |
Recombinant Rat Serine/threonine-protein kinase mTOR (Mtor), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Mtor Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP881349MO CSB-EP881349MO CSB-BP881349MO CSB-MP881349MO CSB-EP881349MO-B |
Recombinant Mouse Serine/threonine-protein kinase mTOR (Mtor) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Mtor ELISA Kit
Mtor ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E09038h | Human mammalian target of rapamyein,mTOR ELISA Kit | serum, plasma, tissue homogenates | 0.39 pg/mL |