Myd88

MYD88，即髓样分化因子88。它是一种在造血干细胞和淋巴组织中表达的转录因子，广泛参与免疫信号的传递。MYD88的来源是人体自身的基因编码，它作为细胞内传递信号的关键衔接蛋白，主要介导多种Toll样受体（TLR）、白细胞介素1受体（IL-1R）及白细胞介素-18受体（IL-18R）的信号传递，在固有免疫中发挥显著作用。MYD88的作用机制涉及到它与各种受体的相互作用，通过其TIR结构域（Toll-白细胞介素1受体域）识别受体激活后的信号，进而招募并激活下游的信号分子，如IRAK（白细胞介素-1受体相关激酶）等。这导致核因子-κB（NF-κB）和MAPK（丝裂原活化蛋白激酶）等转录因子的激活，从而调节炎症因子的表达。MYD88的信号通路包括但不限于NF-κB通路、JAK-STAT3（酪氨酸激酶-信号转导子和转录激活子3）信号通路等，这些通路在细胞增殖、分化以及炎症反应中扮演关键角色。MYD88的生物学意义主要体现在其对固有免疫应答的调控上。它不仅参与病原体识别和炎症反应的启动，还与肿瘤、感染性疾病、自身免疫性疾病等的发病机制密切相关。MYD88依赖的信号通路被认为是这些疾病治疗的潜在靶点。特别是，MYD88基因的某些突变，如L265P，可以导致炎症因子产生增加，这在淋巴浆细胞淋巴瘤等疾病中尤为重要。因此，对MYD88的研究不仅有助于我们理解免疫应答的复杂性，也为开发新的治疗策略提供了可能。

热销产品

Recombinant Human Myeloid differentiation primary response protein MyD88 (MYD88) (CSB-EP859945HU)

验证数据

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP859945HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) MYD88.

MYD88 Antibody (CSB-PA859945LA01HU)

验证数据

Immunofluorescent analysis of HepG2 cells using CSB-PA859945LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human myeloid differentiation factor 88, MyD88 ELISA Kit (CSB-E11747h)

验证数据

货号：CSB-E11747h

规格：96T/48T

灵敏度：0.078 ng/mL

检测范围：0.312ng/mL-20ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Myd88 Antibody

Myd88 Protein

Myd88 ELISA Kit

Myd88 Antibodies

Myd88 for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA003338	MYD88 Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA995911	MYD88 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA859945LA01HU	MYD88 Antibody	Human	ELISA, IF
CSB-PA859945LB01HU	MYD88 Antibody, HRP conjugated	Human	ELISA
CSB-PA859945LC01HU	MYD88 Antibody, FITC conjugated	Human
CSB-PA859945LD01HU	MYD88 Antibody, Biotin conjugated	Human	ELISA

Myd88 Proteins

Myd88 Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP015282MO CSB-EP015282MO CSB-BP015282MO CSB-MP015282MO CSB-EP015282MO-B	Recombinant Mouse Myeloid differentiation primary response protein MyD88 (Myd88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Sus scrofa (Pig)

产品货号	产品名称	来源
CSB-YP015282PI CSB-EP015282PI CSB-BP015282PI CSB-MP015282PI CSB-EP015282PI-B	Recombinant Pig Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Gallus gallus (Chicken)

产品货号	产品名称	来源
CSB-YP015282CH CSB-EP015282CH CSB-BP015282CH CSB-MP015282CH CSB-EP015282CH-B	Recombinant Chicken Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Macaca mulatta (Rhesus macaque)

产品货号	产品名称	来源
CSB-YP015282MOW CSB-EP015282MOW CSB-BP015282MOW CSB-MP015282MOW CSB-EP015282MOW-B	Recombinant Macaca mulatta (Rhesus macaque) Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Ovis aries (Sheep)

产品货号	产品名称	来源
CSB-YP015282SH CSB-EP015282SH CSB-BP015282SH CSB-MP015282SH CSB-EP015282SH-B	Recombinant Sheep Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)

产品货号	产品名称	来源
CSB-YP015282TKY CSB-EP015282TKY CSB-BP015282TKY CSB-MP015282TKY CSB-EP015282TKY-B	Recombinant Takifugu rubripes Myeloid differentiation primary response protein MyD88 (myd88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Salmo salar (Atlantic salmon)

产品货号	产品名称	来源
CSB-YP015282SWI CSB-EP015282SWI CSB-BP015282SWI CSB-MP015282SWI CSB-EP015282SWI-B	Recombinant Salmo salar Myeloid differentiation primary response protein MyD88 (myd88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

产品货号	产品名称	来源
CSB-YP015282MOV CSB-EP015282MOV CSB-BP015282MOV CSB-MP015282MOV CSB-EP015282MOV-B	Recombinant Macaca fascicularis Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Gorilla gorilla gorilla (Lowland gorilla)

产品货号	产品名称	来源
CSB-YP015282GGZ CSB-EP015282GGZ CSB-BP015282GGZ CSB-MP015282GGZ CSB-EP015282GGZ-B	Recombinant Gorilla gorilla gorilla Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Pan troglodytes (Chimpanzee)

产品货号	产品名称	来源
CSB-YP015282EQV CSB-EP015282EQV CSB-BP015282EQV CSB-MP015282EQV CSB-EP015282EQV-B	Recombinant Pan troglodytes Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)

产品货号	产品名称	来源
CSB-YP015282EQU CSB-EP015282EQU CSB-BP015282EQU CSB-MP015282EQU CSB-EP015282EQU-B	Recombinant Pan paniscus Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Pongo pygmaeus (Bornean orangutan)

产品货号	产品名称	来源
CSB-YP015282EXP CSB-EP015282EXP CSB-BP015282EXP CSB-MP015282EXP CSB-EP015282EXP-B	Recombinant Pongo pygmaeus Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

产品货号	产品名称	来源
CSB-YP015282DRI CSB-EP015282DRI CSB-BP015282DRI CSB-MP015282DRI CSB-EP015282DRI-B	Recombinant Cercocebus atys Myeloid differentiation primary response protein MyD88 (Myd88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

产品货号	产品名称	来源
CSB-YP635725XBF CSB-EP635725XBF CSB-BP635725XBF CSB-MP635725XBF CSB-EP635725XBF-B	Recombinant Xenopus tropicalis Myeloid differentiation primary response protein MyD88 (myd88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Bos taurus (Bovine)

产品货号	产品名称	来源
CSB-YP685436BO CSB-EP685436BO CSB-BP685436BO CSB-MP685436BO CSB-EP685436BO-B	Recombinant Bovine Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

产品货号	产品名称	来源
CSB-YP708955OEI CSB-EP708955OEI CSB-BP708955OEI CSB-MP708955OEI CSB-EP708955OEI-B	Recombinant Oncorhynchus mykiss Myeloid differentiation primary response protein MyD88 (myd88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

产品货号	产品名称	来源
CSB-YP730396DIL CSB-EP730396DIL CSB-BP730396DIL CSB-MP730396DIL CSB-EP730396DIL-B	Recombinant Danio rerio Myeloid differentiation primary response protein MyD88 (myd88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Rattus norvegicus (Rat)

产品货号	产品名称	来源
CSB-YP744333RA CSB-EP744333RA CSB-BP744333RA CSB-MP744333RA CSB-EP744333RA-B	Recombinant Rat Myeloid differentiation primary response protein MyD88 (Myd88)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Myd88 Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP859945HU CSB-BP859945HU CSB-MP859945HU CSB-EP859945HU-B	Recombinant Human Myeloid differentiation primary response protein MyD88 (MYD88)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli