Ncr1
NCR1，即自然细胞毒性触发受体1，别名NKp46、CD335、LY94。它是一种免疫球蛋白超家族成员，具有两个细胞外免疫球蛋白样域，属于I型跨膜受体。NCR1由人类19号染色体上的基因编码，位于Leukocyte Receptor Complex (LRC) 区域。NCR1的作用机制是通过与肿瘤细胞或病毒感染细胞表面的配体结合，激活NK细胞的细胞毒性和细胞因子分泌功能，从而参与机体的免疫监视和防御反应 。NCR1在生物学上的意义体现在其对自然杀伤(NK)细胞功能的重要调控作用。NK细胞通过NCR1识别肿瘤或病毒感染细胞，进而发挥杀伤作用。NCR1的表达和功能对于维持机体的免疫平衡和防御能力至关重要。此外，NCR1还可能在其他免疫细胞亚群中发挥作用，如某些类型的T细胞和固有淋巴细胞(ILCs)，这为开发新的免疫治疗策略提供了潜在靶点 。
热销产品
NCR1 Antibody (CSB-PA015549LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human lymph node tissue using CSB-PA015549LA01HU at dilution of 1:100
Immunofluorescent analysis of A549 cells using CSB-PA015549LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Ncr1 Antibodies
Ncr1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA003455 | NCR1 Antibody | Human | WB, ELISA |
| CSB-PA006281 | NCR1 Antibody | Human | WB, ELISA |
| CSB-PA923766 | NCR1 Antibody | Human | ELISA,IHC |
| CSB-PA553079 | NCR1 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA015549LA01HU | NCR1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA015549LB01HU | NCR1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA015549LC01HU | NCR1 Antibody, FITC conjugated | Human | |
| CSB-PA015549LD01HU | NCR1 Antibody, Biotin conjugated | Human | ELISA |
Ncr1 Proteins
Ncr1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015549HU1 CSB-EP015549HU1 CSB-BP015549HU1 CSB-MP015549HU1 CSB-EP015549HU1-B |
Recombinant Human Natural cytotoxicity triggering receptor 1 (NCR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF015549HU | Recombinant Human Natural cytotoxicity triggering receptor 1 (NCR1) | in vitro E.coli expression system |
Ncr1 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015549BO CSB-EP015549BO CSB-BP015549BO CSB-MP015549BO CSB-EP015549BO-B |
Recombinant Bovine Natural cytotoxicity triggering receptor 1 (NCR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Ncr1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015549MO CSB-EP015549MO CSB-BP015549MO CSB-MP015549MO CSB-EP015549MO-B |
Recombinant Mouse Natural cytotoxicity triggering receptor 1 (Ncr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Ncr1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015549MOV CSB-EP015549MOV CSB-BP015549MOV CSB-MP015549MOV CSB-EP015549MOV-B |
Recombinant Macaca fascicularis Natural cytotoxicity triggering receptor 1 (NCR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Ncr1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015549RA CSB-EP015549RA CSB-BP015549RA CSB-MP015549RA CSB-EP015549RA-B |
Recombinant Rat Natural cytotoxicity triggering receptor 1 (Ncr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Ncr1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP619571SVG CSB-EP619571SVG CSB-BP619571SVG CSB-MP619571SVG CSB-EP619571SVG-B |
Recombinant Saccharomyces cerevisiae Niemann-Pick type C-related protein 1 (NCR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
