PVALB
PVALB，即小清蛋白（Parvalbumin）。它是一种低分子量的钙结合蛋白，分子量大约在10-12.5 kDa之间，结构上与钙调蛋白和肌钙蛋白C有关。PVALB在快肌纤维中的含量特别高，但也在其他组织和器官如鱼类的大脑和生殖腺中表达。PVALB的作用机制涉及调节肌肉中的钙离子转换，特别是在快肌纤维中，它帮助控制肌肉收缩的速度和力度。在生物学意义上，PVALB在多种生物过程中发挥作用，包括神经递质释放、肌肉收缩以及作为鱼类中的主要过敏原。超过95%的鱼类引起的食品过敏是由PVALB蛋白引起的。此外，PVALB还可能作为肥胖治疗的潜在新靶点，通过影响M2型巨噬细胞来调节能量消耗和产热。
热销产品
● Recombinant Mouse Parvalbumin alpha (Pvalb)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
验证数据
Immunofluorescence staining of U251 cells with CSB-PA019092HA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Western Blot
Positive WB detected in: Mouse brain tissue, Mouse kidney tissue
All lanes: PVALB antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 13 kDa
Observed band size: 13 kDa
Immunofluorescent analysis of HepG2 cells using CSB-PA019092HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA019092HA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA019092HA01HU at dilution of 1:100
PVALB Antibodies
PVALB for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA019092HA01HU | PVALB Antibody | Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA263723 | PVALB Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA648142 | PVALB Antibody | Human,Mouse,Rat | ELISA,WB |
PVALB Proteins
PVALB Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP019092HU CSB-BP019092HU CSB-MP019092HU CSB-EP019092HU-B |
Recombinant Human Parvalbumin alpha (PVALB) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP019092HU | Recombinant Human Parvalbumin alpha (PVALB) | E.coli |
