SAGE1

div class=margin-large-bottom p class=margin-big-bottomSAGE1（Sarcoma Antigen 1）是一种肿瘤睾丸抗原基因，其在多种肿瘤组织中的表达量通常比癌旁组织高，显示出与细胞增生有密切关系。SAGE1与INTS6（Integrator 6）竞争INTS3（Integrator 3），通过破坏阻碍RNA聚合酶II的“刹车”机制，新形成的INTS3-SAGE1复合物与基因靶标的启动子-近端区域结合，从而激活癌症相关途径中的基因转录。这一过程最终会导致细胞增殖，促进肿瘤的生长和扩散。SAGE1通过影响细胞生长、增殖和分化等关键过程的信号通路，在癌症的发生和发展中发挥重要作用。p h2 class=margin-large-top热销产品h2 pa href=httpswww.dagongcnc.comRecombinant-ProteinsRecombinant-Human-Sarcoma-antigen-1(SAGE1)--partial-677682.htmlRecombinant Human Sarcoma antigen 1 (SAGE1), partialap div class=card card-5n div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-YP20670HUdiv div class=text-center padding p来源：Yeastp div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-EP20670HUdiv div class=text-center padding p来源：E.colip div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-BP20670HUdiv div class=text-center padding p来源：Baculovirusp div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-MP20670HUdiv div class=text-center padding p来源：Mammalian cellp div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-EP20670HU-Bdiv div class=text-center padding p来源：In Vivo Biotinylation in E.colip div div div div br