SESN1
Sestrin-1 is a protein in humans that is encoded by SESN1 gene. Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway.
SESN1 Antibodies
SESN1 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA021095GA01HU | SESN1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA195927 | SESN1 Antibody | Human | ELISA,WB,IHC |
CSB-PA008868 | SESN1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA569570 | SESN1 Antibody | Human,Mouse | ELISA,WB |
CSB-PA021095LA01HU | SESN1 Antibody | Human, Mouse | ELISA, WB, IHC |
CSB-PA021095LC01HU | SESN1 Antibody, FITC conjugated | Human | |
CSB-PA021095LD01HU | SESN1 Antibody, Biotin conjugated | Human | ELISA |
SESN1 Proteins
SESN1 Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP021095MO CSB-EP021095MO CSB-BP021095MO CSB-MP021095MO CSB-EP021095MO-B |
Recombinant Mouse Sestrin-1 (Sesn1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SESN1 Proteins for Xenopus laevis (African clawed frog)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP021095XBE CSB-EP021095XBE CSB-BP021095XBE CSB-MP021095XBE CSB-EP021095XBE-B |
Recombinant Xenopus laevis Sestrin-1 (sesn1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SESN1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP706149MOV CSB-EP706149MOV CSB-BP706149MOV CSB-MP706149MOV CSB-EP706149MOV-B |
Recombinant Macaca fascicularis Sestrin-1 (SESN1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |