SLC7A11
SLC7A11是在KRAS突变后改变表达的蛋白质，可以导致谷胱甘肽代谢的重新布线。SLC7A11是胱氨酸/谷氨酸反转运体系统xc的功能性轻链亚单位。SLC7A11在神经胶质瘤、肝癌、非小细胞肺癌和三阴性乳腺癌等多种癌症类型中过表达，是一个独立的预后因素。SLC7A11还会导致基于谷胱甘肽的耐药性。
CUSABIO-哺乳包膜VIPs平台成功开发SLC7A11全长跨膜蛋白（12次跨膜），展示了完整生物活性。
更多SLC7A11相关阅读：SLC7A11：SLC家族氨基酸转运蛋白，抗铁死亡！肿瘤耐药新方向！
热销产品
Recombinant Human Cystine/glutamate transporter(SLC7A11) (CSB-CF892171HU(A4))
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SLC7A11 at 2 μg/ml can bind Anti-SLC7A11 recombinant antibody (CSB-RA892171MA1HU), the EC50 is 4.482-14.21 ng/mL.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SLC7A11 at 2 μg/ml can bind Anti-SLC7A11 recombinant antibody (CSB-RA892171MA2HU), the EC50 is 117.4-345.4 ng/mL.
SLC7A11 Antibodies
SLC7A11 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA145393 | SLC7A11 Antibody | Human,Mouse | ELISA,WB,IHC |
SLC7A11 Proteins
SLC7A11 Proteins for Pongo abelii (Sumatran orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP735762PYX CSB-EP735762PYX CSB-BP735762PYX CSB-MP735762PYX CSB-EP735762PYX-B |
Recombinant Pongo abelii Cystine/glutamate transporter (SLC7A11), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC7A11 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP892171HU CSB-EP892171HU CSB-BP892171HU CSB-MP892171HU CSB-EP892171HU-B |
Recombinant Human Cystine/glutamate transporter (SLC7A11), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF892171HU(A4) | Recombinant Human Cystine/glutamate transporter (SLC7A11) (Active) | in vitro E.coli expression system |
| CSB-MP892171HU(A4) | Recombinant Human Cystine/glutamate transporter (SLC7A11)-VLPs | Mammalian cell |
SLC7A11 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP894813MO CSB-EP894813MO CSB-BP894813MO CSB-MP894813MO CSB-EP894813MO-B |
Recombinant Mouse Cystine/glutamate transporter (Slc7a11), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
