SV2A
SV2A，即突触囊泡蛋白2A，它是一种在中枢神经系统的神经元中特异性表达的膜蛋白。SV2A主要在突触囊泡上发挥作用，参与调节神经递质的释放和囊泡的循环过程，对维持突触功能至关重要。其作用机制涉及与Ca2+敏感蛋白synaptotagmin-1的相互作用，以及可能的ATP结合和转运功能，影响突触前膜的递质释放概率和囊泡的备释放池大小。SV2A还可能是抗癫痫药物如左乙拉西坦的靶点，通过调节神经递质释放来影响神经系统的兴奋性平衡。在生物学意义上，SV2A的表达变化与癫痫等神经系统疾病的发生发展相关，是研究神经递质释放和相关疾病机制的重要分子。
热销产品
Recombinant Bovine Synaptic vesicle glycoprotein 2A (SV2A), partial (CSB-EP022978BO)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA117413(SV2A Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA117413(SV2A Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
SV2A Antibodies
SV2A for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA117413 | SV2A Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA022978LA01HU | SV2A Antibody | Human | ELISA, IHC |
| CSB-PA022978LB01HU | SV2A Antibody, HRP conjugated | Human | ELISA |
| CSB-PA022978LC01HU | SV2A Antibody, FITC conjugated | Human | |
| CSB-PA022978LD01HU | SV2A Antibody, Biotin conjugated | Human | ELISA |
SV2A Proteins
SV2A Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP022978HU CSB-EP022978HU CSB-BP022978HU CSB-MP022978HU CSB-EP022978HU-B |
Recombinant Human Synaptic vesicle glycoprotein 2A (SV2A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
