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Sell

SELL,即选择素L,是一种细胞表面糖蛋白,属于选择素家族成员之一。它主要在白细胞,尤其是淋巴细胞表面表达,并在血管内皮细胞上也有表达。SELL的作用机制涉及细胞黏附和迁移,通过与血管内皮细胞表面的硫酸肝素等分子相互作用,促进白细胞从血液进入炎症或免疫反应发生的组织。SELL参与的信号通路包括与配体结合后的信号传导,这可能导致细胞内钙离子水平的变化和细胞骨架的重组,从而调节细胞的运动。在生物学意义上,SELL对于淋巴细胞归巢至淋巴器官、参与免疫监视和炎症反应等过程至关重要。SELL的异常表达或功能失调与某些免疫相关疾病,如自身免疫疾病和慢性炎症性疾病的发生发展有关。

热销产品

SELL Antibody (CSB-PA004858)

验证数据

CSB-PA004858

Western Blot analysis of K562 cells using L-Selectin Polyclonal Antibody

Sell Antibodies

Sell for Homo sapiens (Human)

Sell Proteins

Sell Proteins for Bos taurus (Bovine)

Sell Proteins for Homo sapiens (Human)

Sell Proteins for Mus musculus (Mouse)

Sell Proteins for Rattus norvegicus (Rat)

Sell Proteins for Papio hamadryas (Hamadryas baboon)

Sell Proteins for Pongo pygmaeus (Bornean orangutan)

Sell Proteins for Macaca mulatta (Rhesus macaque)

Sell Proteins for Pan troglodytes (Chimpanzee)

Sell ELISA Kit

Sell ELISA Kit for Mus musculus (Mouse)

Sell ELISA Kit for Homo sapiens (Human)

Sell ELISA Kit for Rattus norvegicus (Rat)